Childhood hypopigmented mycosis fungoides: a commonly delayed diagnosis.

Authors:
Ana Gameiro
Ana Gameiro
Coimbra University Hospital
Portugal
Miguel Gouveia
Miguel Gouveia
Católica Lisbon School of Business and Economics
Oscar Tellechea
Oscar Tellechea
Coimbra University Hospital
Portugal
Ana Moreno
Ana Moreno
Ramon y Cajal Hospital
Veguellina de Órbigo | Spain

BMJ Case Rep 2014 Dec 23;2014. Epub 2014 Dec 23.

Coimbra University Hospital, Coimbra, Portugal.

Primary cutaneous lymphomas (PCLs) are exceedingly rare in children and adolescents, with mycosis fungoides (MF) being the most frequent PCL diagnosed in childhood. There are numerous unusual clinical variants of MF, including the hypopigmented type form (HMF). HMF is exceptional overall, but comparatively common among children. We present an 8-year-old boy with a 3-year history of progressive, generalised, scaly, hypopigmented round patches and few erythematous papules. He was first diagnosed with pityriasis alba (PA), and moisturisers were prescribed with no improvement. Skin biopsy showed typical features of MF, and the patient was successfully treated with narrowband ultraviolet B. HMF may simulate atopic dermatitis, PA, pityriasis lichenoides, tinea versicolour, vitiligo, postinflammatory hypopigmentation or leprosy. Therefore, persistent and unusual hypopigmented lesions should be biopsied to rule out this rare variant of MF.
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http://dx.doi.org/10.1136/bcr-2014-208306DOI ListingPossible
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275721PMCFound
December 2014
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