Search Our Scientific Publications & Authors

Eur J Ophthalmol 2021 Apr 16:11206721211010613. Epub 2021 Apr 16.

University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ophthalmology Clinic, Ankara, Turkey.

Aim: To investigate the short-term effects of COVID-19 pandemic related unintended treatment lapses on neovascular age related macular degeneration (nAMD) patients.

Methods: In this prospective cross-sectional study, 140 patients who had at least one anti-vascular endothelial growth factor (VEGF) injection for nAMD within 12 months before COVID-19 pandemic and who had at least 3 months of unintended lapse for control visits during pandemic were recruited and underwent a detailed opthalmological examination and optical coherence tomography imaging.

Results: Of these 140 eyes, 113 (80. Read More

Int Ophthalmol 2021 Apr 8. Epub 2021 Apr 8.

Medical Research Foundation, Shri Bhagwan Mahavir Vitreo-Retinal Services, Sankara Nethralaya, 18 College Road, Chennai, 600006, Tamilnadu, India.

Purpose: To characterize the imaging features in eyes with vitreoretinal lymphoma (VRL) using ultra-widefield fundus photography (UWF-FP), swept-source optical coherence tomography (SSOCT) and fundus autofluorescence (FAF) that are correlated to ongoing treatment with intravitreal Rituximab(IVR).

Methods: Retrospective observational imaging-based study of 15 treatment-naive eyes with VRL treated with IVR. All patients with primary VRL underwent vitreous biopsy using 23/25G microincision vitrectomy system for confirmation of diagnosis. Read More

Eur J Ophthalmol 2021 Mar 25:11206721211005691. Epub 2021 Mar 25.

Army College of Medical Sciences & Base Hospital, New Delhi, India.

Purpose: To report subthreshold micropulse laser as novel treatment modality for exudative maculopathy associated with adult Coats' disease.

Methods: A 27-year old, young male presented with exudative maculopathy in adult onset Coat's disease with profound diminution of vision. Spectral domain-optical coherence tomogram (SD-OCT) revealed macular oedema with significant subfoveal hard exudates with massive subretinal exudations temporal to macula. Read More

Graefes Arch Clin Exp Ophthalmol 2021 Mar 18. Epub 2021 Mar 18.

Association for Innovation and Biomedical Research on Light and Image (AIBILI), Coimbra, Portugal.

Purpose: This study aims to analyze the retinal layers and choroidal thickness in a large set of eyes with early age-related macular degeneration (AMD), in order to detect differences by stage suggestive of early neurodegeneration, and to explore biomarkers of different phenotypes.

Methods: This study is a population-based, cross-sectional study. Patients from the incidence AMD study (NCT02748824) with early AMD (Rotterdam 2a, 2b, 3) were included. Read More

Invest Ophthalmol Vis Sci 2021 Mar;62(3):25

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.

Purpose: To determine the tomographic, angiographic, and histologic changes in the choroid and retina of cynomolgus monkeys after systemic adrenaline and verteporfin photodynamic therapy (vPDT).

Methods: Six cynomolgus monkeys (12 eyes) were treated with vPDT only (n = 2), adrenaline only for eight weeks (n = 2), adrenaline for eight weeks with vPDT at week 4 (n = 4), and adrenaline for 12 weeks and vPDT at week 8 (n = 4). Spectral-domain optical coherence tomography, angiography, and autofluorescence were performed at baseline and every 14 days thereafter until 28 days after adrenaline therapy or vPDT. Read More