Paleogenomics. Genomic structure in Europeans dating back at least 36,200 years.

Science 2014 Nov 6;346(6213):1113-8. Epub 2014 Nov 6.

Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Ă˜ster Voldgade 5-7, 1350 Copenhagen, Denmark.

The origin of contemporary Europeans remains contentious. We obtained a genome sequence from Kostenki 14 in European Russia dating from 38,700 to 36,200 years ago, one of the oldest fossils of anatomically modern humans from Europe. We find that Kostenki 14 shares a close ancestry with the 24,000-year-old Mal'ta boy from central Siberia, European Mesolithic hunter-gatherers, some contemporary western Siberians, and many Europeans, but not eastern Asians. Additionally, the Kostenki 14 genome shows evidence of shared ancestry with a population basal to all Eurasians that also relates to later European Neolithic farmers. We find that Kostenki 14 contains more Neandertal DNA that is contained in longer tracts than present Europeans. Our findings reveal the timing of divergence of western Eurasians and East Asians to be more than 36,200 years ago and that European genomic structure today dates back to the Upper Paleolithic and derives from a metapopulation that at times stretched from Europe to central Asia.

Download full-text PDF

Source
http://www.sciencemag.org/cgi/doi/10.1126/science.aaa0114
Publisher Site
http://dx.doi.org/10.1126/science.aaa0114DOI Listing
November 2014
33 Reads

Publication Analysis

Top Keywords

36200 years
12
years ago
8
genomic structure
8
find kostenki
8
european mesolithic
4
siberia european
4
dna contained
4
structure today
4
hunter-gatherers contemporary
4
western siberians
4
siberians europeans
4
reveal timing
4
contemporary western
4
central siberia
4
mesolithic hunter-gatherers
4
boy central
4
close ancestry
4
shares close
4
upper paleolithic
4
kostenki neandertal
4

Similar Publications