Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort.

Eur J Epidemiol 2015 Jan 7;30(1):57-70. Epub 2014 Nov 7.

Department of Community Medicine, UiT-The Arctic University of Norway, Tromsö, Norway,

Fish is a source of important nutrients and may play a role in preventing heart diseases and other health outcomes. However, studies of overall mortality and cause-specific mortality related to fish consumption are inconclusive. We examined the rate of overall mortality, as well as mortality from ischaemic heart disease and cancer in relation to the intake of total fish, lean fish, and fatty fish in a large prospective cohort including ten European countries. More than 500,000 men and women completed a dietary questionnaire in 1992-1999 and were followed up for mortality until the end of 2010. 32,587 persons were reported dead since enrolment. Hazard ratios and their 99% confidence interval were estimated using Cox proportional hazard regression models. Fish consumption was examined using quintiles based on reported consumption, using moderate fish consumption (third quintile) as reference, and as continuous variables, using increments of 10 g/day. All analyses were adjusted for possible confounders. No association was seen for fish consumption and overall or cause-specific mortality for both the categorical and the continuous analyses, but there seemed to be a U-shaped trend (p < 0.000) with fatty fish consumption and total mortality and with total fish consumption and cancer mortality (p = 0.046).

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-014-9966-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356893PMC
January 2015
127 Reads

Publication Analysis

Top Keywords

fish consumption
28
fish
11
mortality
9
cause-specific mortality
8
fatty fish
8
total fish
8
consumption
7
men women
4
500000 men
4
analyses adjusted
4
countries 500000
4
g/day analyses
4
increments g/day
4
completed dietary
4
european countries
4
questionnaire 1992-1999
4
women completed
4
dietary questionnaire
4
including ten
4
fish fatty
4

References

(Supplied by CrossRef)

G Dunn et al.
J Biopharm Stat 2007

G Dunn et al.
Stat Methods Med Res 1999

Similar Publications