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One problem two issues! Left ventricular systolic and diastolic dysfunction in aortic stenosis.

Authors:
Maqsood M Elahi Anthony Chuang Michael J Ewing Charles H Choi Peter W Grant Bashir M Matata

Ann Transl Med 2014 Jan;2(1):10

1 Division of Cardiothoracic Surgery, Department of Surgery, Texas A & M Health Science Center at Scott & White Memorial Hospital, Temple, TX, USA ; 2 Division of Cardiothoracic Surgery, Prince of Wales & Sydney Children's Hospital, Barker Street, Randwick, Sydney, NSW, Australia ; 3 Liverpool Heart and Chest Hospital, NHS Foundation Trust, Liverpool, UK.

Reports suggested that immediate post-aortic valve replacement (AVR); left ventricular (LV) dysfunction may be an important risk for morbidity and mortality in patients requiring positive inotropic support. Several factors have been identified as significant prognostic factors i.e., LV systolic dysfunction, LV diastolic dysfunction (LV-DD), heart failure and myocardial infarction (MI). Specific to pathophysiological changes associated with AS, markers of systolic LV function (e.g., LVEF) have been extensively studied in management, yet only a few studies have analysed the association between LV-DD and immediate post-operative LV dysfunction This review brings together the current body of evidence on this issue.

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http://dx.doi.org/10.3978/j.issn.2305-5839.2013.06.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200657PMC
January 2014

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