Heart 2015 Feb 16;101(3):201-8. Epub 2014 Oct 16.
Health Economics and Health Technology Assessment, Institute of Health & Wellbeing, University of Glasgow, Glasgow, UK.
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Open Heart 2016 10;3(1):e000140. Epub 2016 Jun 10.
Health Economics and Health Technology Assessment , Institute of Health & Wellbeing, University of Glasgow , Glasgow , UK.
Objectives: This is the second of the two papers introducing a cardiovascular disease (CVD) policy model. The first paper described the structure and statistical underpinning of the state-transition model, demonstrating how life expectancy estimates are generated for individuals defined by ASSIGN risk factors. This second paper describes how the model is prepared to undertake economic evaluation. Read More
J Manag Care Pharm 2013 Mar;19(2):102-14
Department of Social, Behavioral, and Administrative Science, Touro University College of Pharmacy, 1310 Club Dr., Mare Island, Vallejo, CA 94592, USA.
Background: It has been demonstrated in previous studies that pharmacist management of patients with type 2 diabetes mellitus (T2DM) in the outpatient setting not only improves diabetes-related clinical outcomes such as hemoglobin A1c but also blood pressure (BP), total cholesterol (TC), and quality of life. Improved control of BP and TC has been shown to reduce the risks of cardiovascular disease (CVD), which has placed a heavy economic burden on the health care system. However, no study has evaluated the cost-effectiveness of pharmacist intervention programs with respect to the long-term preventive effects on CVD outcomes among T2DM patients. Read More
Health Technol Assess 2007 Apr;11(14):1-160, iii-iv
School of Health and Related Research (ScHARR), University of Sheffield, UK.
Objectives: To evaluate the clinical effectiveness and cost-effectiveness of statins for the primary and secondary prevention of cardiovascular events in adults with, or at risk of, coronary heart disease (CHD).
Data Sources: Electronic databases were searched between November 2003 and April 2004.
Review Methods: A review was undertaken to identify and evaluate all literature relating to the clinical and cost effectiveness of statins in the primary and secondary prevention of CHD and cardiovascular disease (CVD) in the UK. Read More
PLoS Med 2012 27;9(12):e1001361. Epub 2012 Dec 27.
Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
Background: Physicians need to inform asymptomatic individuals about personalized outcomes of statin therapy for primary prevention of cardiovascular disease (CVD). However, current prediction models focus on short-term outcomes and ignore the competing risk of death due to other causes. We aimed to predict the potential lifetime benefits with statin therapy, taking into account competing risks. Read More