J Surg Oncol 2015 Jan 2;111(1):18-23. Epub 2014 Sep 2.
Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Department of Surgery, Women's College Hospital, Toronto, Ontario, Canada; Department of Surgery, University Health Network, Toronto, Ontario, Canada.
Using genetic information to make medical decisions and tailor treatments to individuals will likely provide major benefits and become an important part of health care. Surgical oncologists must ethically apply scientific genetic information in a complex and evolving environment to the benefit of their patients. In this review we address ethical issues associated with: indications for genetic testing, informed consent for testing and therapy, confidentiality, targeted therapy, prophylactic surgery, and genetic testing in children.