Differing tales of two patients after receiving a kidney transplant from a donor with disseminated intravascular coagulation.

Authors:
Pradeep V Kadambi
Pradeep V Kadambi
University of Arizona
United States
Mohammad Almiani
Mohammad Almiani
University of Chicago
Michelle A Josephson
Michelle A Josephson
University of Chicago
Chicago | United States

Case Rep Transplant 2014 30;2014:754256. Epub 2014 Jun 30.

University of Chicago, 5841 S Maryland Avenue, MC 5100, Chicago, IL 60637, USA.

In order to decrease the time on the deceased donor kidney wait list and to have more organs available, criteria for acceptable organs for transplant could be made less stringent. There are reports of successful recipient outcomes using kidney donors presenting with disseminated intravascular coagulation (DIC). We report a unique circumstance where two patients received kidneys from the same deceased donor who had DIC; one patient developed thrombotic microangiopathy (TMA) while the other did not. This difference in outcome may indicate that both donor and recipient factors contribute to the development of posttransplant TMA.

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Source
http://dx.doi.org/10.1155/2014/754256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100278PMC

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July 2014
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References

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1994
Article in Kidney International
Kidney International 1986
Article in The World Journal of Nephrology
The World Journal of Nephrology 2013

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