Macromolecule loading into spherical, elliptical, star-like and cubic calcium carbonate carriers.

Chemphyschem 2014 Sep 10;15(13):2817-22. Epub 2014 Jul 10.

BIOtech research center, Department of Physics, University of Trento via delle Regole 101, 38123 Mattarello (Italy), Fax: (+39) 0461 283659; Shubnikov Institute of Crystallography Russian Academy of Science, Leninskii prospekt 59, Moscow 119333 (Russia).

We fabricated calcium carbonate particles with spherical, elliptical, star-like and cubical morphologies by varying relative salt concentrations and adding ethylene glycol as a solvent to slow down the rate of particle formation. The loading capacity of particles of different isotropic (spherical and cubical) and anisotropic (elliptical and star-like) geometries is investigated, and the surface area of such carriers is analysed. Potential applications of such drug delivery carriers are highlighted.

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Source
http://doi.wiley.com/10.1002/cphc.201402136
Publisher Site
http://dx.doi.org/10.1002/cphc.201402136DOI Listing
September 2014

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