Biodegradable ethylene-bis(propyl)disulfide-based periodic mesoporous organosilica nanorods and nanospheres for efficient in-vitro drug delivery.

Authors:
Jonas Croissant
Jonas Croissant
Smart Hybrid Materials Laboratory
United States
Audrey Gallud
Audrey Gallud
Nanosafety & Nanomedicine Laboratory
France
Laurence Raehm
Laurence Raehm
Institut Charles Gerhardt Montpellier
Montpellier | France
Philippe Trens
Philippe Trens
Laboratoire de Matériaux Catalytiques et Catalyse en Chimie Organique
France
Marie Maynadier
Marie Maynadier
NanoMedSyn
Montpellier | France

Adv Mater 2014 Sep 17;26(35):6174-80. Epub 2014 Jul 17.

Institut Charles Gerhardt Montpellier, UMR-5253 CNRS-UM2-ENSCM-UM1cc 1701, Place Eugène Bataillon, F-34095, Montpellier cedex 05, France.

Periodic mesoporous organosilica nanorods and nanospheres are synthesized from 1,4-bis(triethoxysilyl)ethylene and bis(3-ethoxysilylpropyl)disulfide. The nanosystems present the long-range order of the hexagonal nanostructure. They are degraded in simulated physiological conditions. The loading and release of doxorubicin with these nanosystems are both pH dependent. These nanoparticles are endocytosed by breast cancer cells and are very efficient for doxorubicin delivery in these cells.

Download full-text PDF

Source
http://dx.doi.org/10.1002/adma.201401931DOI Listing

Still can't find the full text of the article?

We can help you send a request to the authors directly.
September 2014
45 Reads
8 Citations
17.493 Impact Factor

Article Mentions


Provided by Crossref Event Data
twitter
Twitter: Croissant_g
July 19, 2018, 7:18 pm EST

Publication Analysis

Top Keywords

mesoporous organosilica
8
organosilica nanorods
8
periodic mesoporous
8
nanorods nanospheres
8
order hexagonal
4
endocytosed breast
4
hexagonal nanostructure
4
nanostructure degraded
4
long-range order
4
breast cancer
4
14-bistriethoxysilylethylene bis3-ethoxysilylpropyldisulfide
4
bis3-ethoxysilylpropyldisulfide nanosystems
4
nanosystems long-range
4
nanoparticles endocytosed
4
degraded simulated
4
release doxorubicin
4
conditions loading
4
loading release
4
physiological conditions
4
doxorubicin nanosystems
4

References

(Supplied by CrossRef)
Article in Phys. Chem. Chem. Phys.
De Canck et al.
Phys. Chem. Chem. Phys. 2013
Article in Z. Anorg. Allg. Chem.
Martens et al.
Z. Anorg. Allg. Chem. 2014
Article in Chem. Eng. J.
Otero et al.
Chem. Eng. J. 2013
Article in Chem. Eur. J.
Gao et al.
Chem. Eur. J. 2014
Article in Adv. Synth. Catal.
Grüning et al.
Adv. Synth. Catal. 2014
Article in J. Mater. Chem.
Melero et al.
J. Mater. Chem. 2007
Article in Chem. Commun.
Karimi et al.
Chem. Commun. 2011
Article in Cat. Sci. Tech.
Karimi et al.
Cat. Sci. Tech. 2012
Article in Angew. Chem. Int. Ed.
Borah et al.
Angew. Chem. Int. Ed. 2012
Article in Micro. Meso. Mater.
Lin et al.
Micro. Meso. Mater. 2009
Article in Chem. Eur. J.
Wu et al.
Chem. Eur. J. 2013

Similar Publications