Breastfeeding versus formula-feeding and girls' pubertal development.

Matern Child Health J 2015 Mar;19(3):519-27

School of Public Health, University of California, Berkeley, Berkeley, CA, USA,

To examine the association of breastfeeding or its duration with timing of girls' pubertal onset, and the role of BMI as a mediator in these associations. A population of 1,237 socio-economically and ethnically diverse girls, ages 6-8 years, was recruited across three geographic locations (New York City, Cincinnati, and the San Francisco Bay Area) in a prospective study of predictors of pubertal maturation. Breastfeeding practices were assessed using self-administered questionnaire/interview with the primary caregiver. Girls were seen on at least annual basis to assess breast and pubic hair development. The association of breastfeeding with pubertal timing was estimated using parametric survival analysis while adjusting for body mass index, ethnicity, birth-weight, mother's education, mother's menarcheal age, and family income. Compared to formula fed girls, those who were mixed-fed or predominantly breastfed showed later onset of breast development [hazard ratios 0.90 (95 % CI 0.75, 1.09) and 0.74 (95 % CI 0.59, 0.94), respectively]. Duration of breastfeeding was also directly associated with age at onset of breast development (p trend = 0.008). Associations between breastfeeding and pubic hair onset were not significant. In stratified analysis, the association of breastfeeding and later breast onset was seen in Cincinnati girls only. The association between breast feeding and pubertal onset varied by study site. More research is needed about the environments within which breastfeeding takes place in order to better understand whether infant feeding practices are a potentially modifiable risk factor that may influence age at onset of breast development and subsequent risk for disease in adulthood.

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http://dx.doi.org/10.1007/s10995-014-1533-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263683PMC
March 2015
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References

(Supplied by CrossRef)

SE Anderson et al.
Pediatrics 2003

J Downing et al.
BMC Public Health 2009

MS Golub et al.
Pediatrics 2008

FF Kadlubar et al.
Cancer Epidemiology, Biomarkers & Prevention 2003

L Bernstein et al.
Journal of Mammary Gland Biology and Neoplasia 2002

A Mouritsen et al.
International Journal of Andrology 2010

J Toppari et al.
Molecular and Cellular Endocrinology 2010

G Cheng et al.
Journal of Nutrition 2010

M Maisonet et al.
Pediatrics 2010

N Karaolis-Danckert et al.
American Journal of Clinical Nutrition 2009

MK Kwok et al.
Pediatrics 2012

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