J Diabetes Investig 2013 Nov 11;4(6):679-80. Epub 2013 Jun 11.
Department of Metabolic Medicine Graduate School of Medicine Osaka University Suita Japan.
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Endocr Pract 2008 Apr;14(3):337-9
Department of Internal Medicine, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45208, USA.
Objective: To identify patients with an inaccurate diagnosis of hypoglycemia and discuss predisposing factors.
Methods: We describe our patient's clinical presentation, laboratory work-up, hospital course, and follow-up and review similar cases from the literature.
Results: A 27-year-old woman with Raynaud phenomenon was admitted because of symptomatic hypoglycemia. Read More
Yonsei Med J 2013 Sep;54(5):1289-92
Department of Internal Medicine, Gyeongsang National University School of Medicine, 79 Gangnam-ro, Jinju 660-702, Korea.
We describe herein a case of life-threatening hypoglycemia due to spurious elevation of glucose concentration during the administration of ascorbic acid in a type 2 diabetic patient. A 31-year-old female was admitted for proliferative diabetic retinopathy treatment and prescribed high dose ascorbic acid. During hospitalization, she suddenly lost her consciousness and her glucose concentration was 291 mg/dL, measured using self-monitoring blood glucose (SMBG) device, while venous blood glucose concentration was 12 mg/dL. Read More
Diabetes 1983 Nov;32(11):1078-81
It has recently been reported that glucose and its analogues inhibit in vitro ascorbic acid transport across the cell membrane of polymorphonuclear leukocytes and fibroblasts. We have studied the effect of in vivo hyperglycemia on the intracellular ascorbic acid level of mononuclear leukocytes in normal and diabetic human subjects. Administration of an intravenous glucose load resulted in a prompt decrease of mononuclear leukocyte ascorbic acid level in the normal subjects. Read More
Lab Med 2014 ;45(4):e156-7
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA Clinical Laboratories, University of Pittsburgh Medical Center Presbyterian and Shadyside Hospitals, Pittsburgh, PA McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA
Herein, we present a case of pseudohypoglycemia induced by hypothermia in an 83-year-old white man in whom glucose levels between venous and capillary blood were discrepant. Although pseudohypoglycemia has been reported in the literature, it is under-recognized among health care professionals and laboratorians. Health care professionals may encounter pseudohypoglycemia using glucose meters; the potentially inaccuracy of glucose meter results for critically ill patients has been intensely debated recently. Read More