Knee Surg Sports Traumatol Arthrosc 2015 Aug 26;23(8):2218-2229. Epub 2014 Apr 26.
Institute of Orthopaedic Research and Biomechanics, Centre of Musculoskeletal Research, University of Ulm, Helmholtzstraße 14, 89081, Ulm, Germany.
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Am J Sports Med 2015 Oct 21;43(10):2528-37. Epub 2015 Aug 21.
Department of Orthopaedic Surgery, Rutgers Biomedical and Health Sciences-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA Department of Biomedical Engineering, Rutgers-The State University of New Jersey, Piscataway, New Jersey, USA
Background: Meniscus injuries in the United States result in an estimated 850,000 surgical procedures each year. Although meniscectomies are the most commonly performed orthopaedic surgery, little advancement has been made in meniscus replacement and regeneration, and there is currently no total meniscus replacement device approved by the Food and Drug Administration.
Hypothesis: A novel fiber-reinforced meniscus scaffold can be used as a functional total meniscus replacement. Read More
Knee Surg Sports Traumatol Arthrosc 2016 May 23;24(5):1478-84. Epub 2015 Aug 23.
Department of Orthopedics and Rheumatology, University Hospital Marburg, Baldingerstrasse, 35043, Marburg, Germany.
Purpose: The preservation of meniscal structure and function after segmental meniscal loss is of crucial importance to prevent early development of osteoarthritis. Implantation of artificial meniscal implants has been reported as a feasible treatment option. The purpose of this study was to assess the clinical and magnetic resonance imaging (MRI) results 4 years after implantation of a polyurethane scaffold for chronic segmental medial meniscus deficiency following partial medial meniscectomy. Read More
Am J Sports Med 2016 10 18;44(10):2615-2621. Epub 2016 Jul 18.
Department of Physiotherapy and Orthopaedics, Faculty of Medicine, Ghent University, Ghent, Belgium.
Background: A biodegradable polyurethane scaffold was designed to fulfill a challenging clinical need in the treatment of patients with painful, irreparable partial meniscal defects.
Hypothesis: The use of an acellular polyurethane scaffold for new tissue generation in irreparable, partial meniscal defects provides both midterm pain relief and improved functionality.
Study Design: Case series; Level of evidence, 4. Read More
Knee Surg Sports Traumatol Arthrosc 2012 Sep 17;20(9):1822-30. Epub 2011 Nov 17.
Department of Orthopaedics and Rheumatology, University Hospital Marburg, Baldingerstrasse, 35043 Marburg, Germany.
Purpose: Meniscal loss is associated with an increased risk of developing osteoarthritis. Tissue engineering solutions, which include the development of novel material scaffolds, are being utilised to aid the regeneration of meniscal tissue. The purpose of this study was to monitor the safety profile and the short-term efficacy of a novel polyurethane meniscal scaffold in the treatment of patients with painful knees following partial medial meniscectomy. Read More