Knee Surg Sports Traumatol Arthrosc 2015 Aug 26;23(8):2218-2229. Epub 2014 Apr 26.
Institute of Orthopaedic Research and Biomechanics, Centre of Musculoskeletal Research, University of Ulm, Helmholtzstraße 14, 89081, Ulm, Germany.
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Materials (Basel) 2018 Sep 3;11(9). Epub 2018 Sep 3.
Department of Information Engineering, Electronics and Telecommunications (DIET), Sapienza University of Rome, 00184 Rome, Italy.
This paper illustrates how the penetration of electromagnetic waves in lossy media strongly depends on the waveform and not only on the media involved. In particular, the so-called inhomogeneous plane waves are compared against homogeneous plane waves illustrating how the first ones can generate deep penetration effects. Moreover, the paper provides examples showing how such waves may be practically generated. Read More
Biochemistry 2015 Mar 17;54(12):2149-59. Epub 2015 Mar 17.
Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, India.
Thalidomides were initially thought to be broad-range drugs specifically for curing insomnia and relieving morning sickness in pregnant women. However, its use was discontinued because of a major drawback of causing teratogenicity. In this study, we found that a thalidomide derivative, 5-hydroxy-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione (5HPP-33), inhibited the proliferation of MCF-7 with a half-maximal inhibitory concentration of 4. Read More
Eur J Pharmacol 2014 Apr 11;729:138-43. Epub 2014 Feb 11.
PROFISIO, Universidad Nacional de Rosario, Argentina; VA Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA; Department of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Consejo Nacional de Investigaciones Cientificas y Tecnicas, Argentina. Electronic address:
L-arginine administration decreases mean arterial blood pressure (MABP), presumably by excess nitric oxide (NO) synthesis. However, some reports indicate that d-arginine, not a substrate of NO synthase (NOS), also induces hypotension. To clarify this phenomenon, the hemodynamic effects of L- and D-arginine and their modification by NOS inhibition with L-nitroarginine methyl ester (L-NAME) were assessed. Read More
JSLS 2013 Jul-Sep;17(3):423-8
Section of Minimally Invasive Urology, Warren Alpert Medical School of Brown University, 2 Dudley St, Ste 174, Providence, RI 02905, USA.
Introduction: Technological advancements have reduced the morbidity associated with cryosurgery, leading to an increased interest in this modality for the treatment of organ-confined prostate cancer. In this study, we critically examine the current role of cryoablation of the prostate to better understand how to counsel patients regarding this treatment option.
Methods: A database was compiled over a 3-year period (2008-2011) of 30 patients who underwent cryoablation for organ-confined prostate cancer. Read More
J Pharm Biomed Anal 2013 Nov 12;85:108-17. Epub 2013 Jul 12.
US Food and Drug Administration, CDER, Division of Pharmaceutical Analysis, St. Louis, MO 63101, USA.
Tacrolimus (FK506) is a potent, narrow therapeutic index, immunosuppressive drug used to avoid organ rejection in patients that have undergone organ transplantation. Recent clinical reports suggested a significant reduction in the tacrolimus concentration/dose ratio in the plasma of liver and kidney recipients when the reference listed drug was substituted with a generic drug. In response to these concerns about switching between tacrolimus from different approved manufacturers during treatment, the FDA initiated purity, potency and quality studies of the innovator and generic tacrolimus products available in the US marketplace. Read More