Evidence of adaptive evolution of alpine pheasants to high-altitude environment from mitogenomic perspective.

Mitochondrial DNA A DNA Mapp Seq Anal 2016 4;27(1):455-62. Epub 2015 Sep 4.

a College of Animal Science and Technology, Sichuan Agricultural University , Ya'an , China and.

Adaptive evolutions to high-altitude adaptation have been intensively studied in mammals. However, considering the additional vertebrate groups, new perception regarding selection challenged by high-altitude stress on mitochondrial genome can be gained. To test this hypothesis, we compiled and analyzed the mitochondrial genomes of 5 alpine pheasants and 12 low-altitude species in Phasianidae. The results that evolutionary rates of ATP6 and ND6 showing significant fluctuation among branches when involved with five alpine pheasants revealed both genes might have implications with adapting to highland environment. The radical physico-chemical property changes identified by the modified MM01 model, including composition (C) and equilibrium constant (ionization of COOH) (Pk') in ATP6 and beta-structure tendencies (Pβ), Pk', and long-range non-bonded energy (El) in ND6, suggested that minor overall adjustments in size, protein conformation and relative orientation of reaction interfaces have been optimized to provide the ideal environments for electron transfer, proton translocation and generation of adenosine triphosphate (ATP). Additionally, three unique substitution sites were identified under selection in ND6, which could be potentially important adaptive changes contributing to cellular energy production. Our findings suggested that adaptive evolution may occur in alpine pheasants, which are an important complement to the knowledge of genetic mechanisms against the high-altitude environment in non-mammal animals.

Download full-text PDF

Source
http://dx.doi.org/10.3109/19401736.2014.900667DOI Listing
September 2016
62 Reads

Publication Analysis

Top Keywords

alpine pheasants
16
adaptive evolution
8
high-altitude environment
8
radical physico-chemical
4
physico-chemical property
4
property changes
4
environment radical
4
unique substitution
4
adapting highland
4
highland environment
4
three unique
4
additionally three
4
mm01 model
4
model including
4
triphosphate atp
4
atp additionally
4
modified mm01
4
implications adapting
4
identified modified
4
changes identified
4

References

(Supplied by CrossRef)

Bigham AW et al.
Hum Genomics 2009

Chiappe LM et al.
2007

Similar Publications