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Environ Pollut 2021 Feb 19;278:116791. Epub 2021 Feb 19.

Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China; Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China; Guangxi Key Laboratory for Genomic and Personalized Medicine, Nanning, Guangxi, China; Guangxi Collaborative Innovation Center for Genomic and Personalized Medicine, Nanning, Guangxi, China; Guangxi Colleges and Universities Key Laboratory of Prevention and Control of Highly Prevalent Diseases, Guangxi Medical University, Nanning, Guangxi, China; Department of Public Health, School of Medicine, Guangxi University of Science and Technology, Liuzhou, Guangxi, China. Electronic address:

Previous studies have reported metals exposure contribute to the change of fasting blood glucose (FBG) level. However, the roles of reproductive hormones in their associations have not been fully elucidated. The aim of the study is to investigate the associations of multiple serum metals with reproductive hormones, and to further explore potential roles of reproductive hormones in relationships between metals exposure and FBG level. Read More

Front Med (Lausanne) 2021 15;8:627725. Epub 2021 Feb 15.

Institute of Pain Medicine and Special Environmental Medicine, Nantong University, Nantong, China.

Chronic itch is a common distressing symptom of many diseases, which reduced patient's quality of life. The mechanistic study on itch and screening for new anti-itch drugs require the development of new pre-clinical itch animal models. Herein, we established an acute itch model by intradermal (i. Read More

Mitochondrial DNA B Resour 2021 Feb 9;6(2):468-469. Epub 2021 Feb 9.

Co-Innovation Center for Sustainable Forestry in Southern China, College of Biology and the Environment, Nanjing Forestry University, Nanjing, China.

Holly ( L.) is a woody dioecious genus cultivated as pharmaceutical, ornamentals, and industrial materials. (H. Read More

Nanoscale 2021 Feb 18;13(8):4562-4568. Epub 2021 Feb 18.

The State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.

Environment-friendly high color purity blue zinc selenide (ZnSe) quantum dot-based light-emitting diodes (QLEDs) are promising candidates in next-generation display applications. However, due to the large bandgap of ZnSe (2.7 eV), the reported electroluminescence (EL) wavelengths of ZnSe QLEDs are mainly located within the range from purple to violet blue, and preparing blue emitting (>445 nm) ZnSe QLEDs remains challenging. Read More

BMC Genomics 2021 Feb 12;22(1):118. Epub 2021 Feb 12.

Department of Animal Science, University of California - Davis, Davis, CA, USA.

Background: The homologous recombination (HR) pathway is largely inactive in early embryos prior to the first cell division, making it difficult to achieve targeted gene knock-ins. The homology-mediated end joining (HMEJ)-based strategy has been shown to increase knock-in efficiency relative to HR, non-homologous end joining (NHEJ), and microhomology-mediated end joining (MMEJ) strategies in non-dividing cells.

Results: By introducing gRNA/Cas9 ribonucleoprotein complex and a HMEJ-based donor template with 1 kb homology arms flanked by the H11 safe harbor locus gRNA target site, knock-in rates of 40% of a 5. Read More