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Anim Reprod Sci 2021 Mar 27;228:106747. Epub 2021 Mar 27.

Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA; School of Veterinary Medicine, Utah State University, Logan, UT, USA. Electronic address:

This study was conducted to determine whether T cell populations are responsible for modulating placental development during gestation in cattle. It was hypothesized that CD4+CD25+ and γ/δ+ T cells modulate gene expression, based on mRNA transcript abundances, and promote proliferation and survival of trophoblast cells. Peripheral blood was collected from cows at 160 to 180 days of gestation and non-pregnant cows, T cell populations CD8+, CD4+, CD4+CD25+, CD24+CD25-, and γ/δ+ T cells were isolated, cultured for 48 h, and supernatant was collected. Read More

Leuk Res 2021 Mar 31;105:106570. Epub 2021 Mar 31.

Department of Pediatrics, National Defense Medical College, Tokorozawa, Saitama-ken, Japan.

Transient abnormal myelopoiesis (TAM) in neonates with Down syndrome, which spontaneously resolves within several weeks or months after birth, may represent a special form of leukemia developing in the fetal liver (FL). To explore the role of hepatoblasts, one of the major constituents of the FL hematopoietic microenvironment, in the pathogenesis of TAM, we investigated the influence of a human hepatoblastoma cell line, HUH-6, on the in vitro growth and differentiation of TAM blasts. In a coculture system with membrane filters, which hinders cell-to-cell contact between TAM blasts and HUH-6 cells, the growth and megakaryocytic differentiation of TAM blast progenitors were increased in the presence of HUH-6 cells. Read More

Neuroimage Clin 2021 Mar 29;30:102650. Epub 2021 Mar 29.

Centre for the Developing Brain, King's College London, London, UK.

Background: Infants born preterm are at increased risk of neurological complications resulting in significant morbidity and mortality. The exact mechanism and the impact of antenatal factors has not been fully elucidated, although antenatal infection/inflammation has been implicated in both the aetiology of preterm birth and subsequent neurological sequelae. It is therefore hypothesized that processes driving preterm birth are affecting brain development in utero. Read More

J Gynecol Obstet Hum Reprod 2021 Apr 7:102137. Epub 2021 Apr 7.

Department of Nutrition and Dietetics, Faculty of Health Sciences, Ankara University, Ankara, Turkey Postal Code: 06290, Phone Number: +90 0312 381 23 50.

Objective: Anemia and iron deficiency during pregnancy influence maternal and fetal health, birth outcomes, and the risk of chronic disease in offspring. This study aimed to examine the association with sociodemographic, maternal factors, supplement use and dietary intakes, and anemia and iron deficiency in pregnancy.

Methods: A cross-sectional study was conducted on 165 pregnant women aged between 19-45 years who were interviewed, and dietary intake was assessed by 24-hours dietary recall, supplement records and food frequency questionnaire. Read More

BJOG 2021 Apr 9. Epub 2021 Apr 9.

Department of Obstetrics and Gynecology Foothills Medical Center, Alberta Health Services, Canada.

Objectives: To evaluate the recurrence risk of stillbirth.

Design: Retrospective cohort study.

Setting And Population: All births 1992-2017, Alberta, Canada METHODS: Retrospective cohort study. Read More