ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models.

Authors:
Prof. Dr. Johann Bauersachs, MD
Prof. Dr. Johann Bauersachs, MD
Hannover Medical School
Cardiology, Intensive Care
Hannover | Germany
Angela Clerk
Angela Clerk
Imperial College London
United Kingdom
Stephane Heymans
Stephane Heymans
Center for Heart Failure Research
Houston | United States

Eur J Heart Fail 2014 May 23;16(5):509-18. Epub 2014 Feb 23.

Department of Physiology and Cardiothoracic Surgery, Faculty of Medicine, University of Porto, Al. Prof. Hernani Monteiro, 4200 319, Porto, Portugal.

The right ventricle has become an increasing focus in cardiovascular research. In this position paper, we give a brief overview of the specific pathophysiological features of the right ventricle, with particular emphasis on functional and molecular modifications as well as therapeutic strategies in chronic overload, highlighting the differences from the left ventricle. Importantly, we put together recommendations on promising topics of research in the field, experimental study design, and functional evaluation of the right ventricle in experimental models, from non-invasive methodologies to haemodynamic evaluation and ex vivo set-ups.

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Source
http://dx.doi.org/10.1002/ejhf.66DOI Listing
May 2014
32 Reads
3 Citations
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References

(Supplied by CrossRef)
Pulmonary circulation at exercise
Naeije et al.
Comp Physiol 2012

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