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Bifurcation analysis of "synchronization fluctuation": a diagnostic measure of brain epileptic states.

Authors:
Fatemeh Bakouie Keivan Moradi Shahriar Gharibzadeh Farzad Towhidkhah

Front Comput Neurosci 2014 6;8:11. Epub 2014 Feb 6.

Cybernetics and Modeling of Biological Systems Laboratory, Biomedical Engineering Faculty, Amirkabir University of Technology Tehran, Iran.

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http://dx.doi.org/10.3389/fncom.2014.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915881PMC
February 2014

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Multimodal FDG-PET and EEG assessment improves diagnosis and prognostication of disorders of consciousness.

Authors:
Bertrand Hermann Johan Stender Marie-Odile Habert Aurélie Kas Mélanie Denis-Valente Federico Raimondo Pauline Pérez Benjamin Rohaut Jacobo Diego Sitt Lionel Naccache

Neuroimage Clin 2021 Feb 23;30:102601. Epub 2021 Feb 23.

Institut du Cerveau et de la Moelle épinière - ICM, Inserm U1127, CNRS UMR 7225, F-75013 Paris, France; Faculté de Médecine Pitié-Salpêtrière, Sorbonne Universités, UPMC Université Paris 06, Paris, France; Service de Neurophysiologie, Groupe hospitalier Pitié-Salpêtrière, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France.

Introduction: Functional brain-imaging techniques have revealed that clinical examination of disorders of consciousness (DoC) can underestimate the conscious level of patients. FDG-PET metabolic index of the best preserved hemisphere (MIBH) has been reported as a promising measure of consciousness but has never been externally validated and compared with other brain-imaging diagnostic procedures such as quantitative EEG.

Methods: FDG-PET, quantitative EEG and cognitive evoked potential using an auditory oddball paradigm were performed in minimally conscious state (MCS) and vegetative state (VS) patient. Read More

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February 2021
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Non-credible symptom report in the clinical evaluation of adult ADHD: development and initial validation of a new validity index embedded in the Conners' adult ADHD rating scales.

Authors:
Miriam Becke Lara Tucha Matthias Weisbrod Steffen Aschenbrenner Oliver Tucha Anselm B M Fuermaier

J Neural Transm (Vienna) 2021 Mar 2. Epub 2021 Mar 2.

Department of Clinical and Developmental Neuropsychology, Faculty of Behavioural and Social Sciences, University of Groningen, Grote Kruisstraat 2/1, 9712 TS, Groningen, The Netherlands.

As attention-deficit/hyperactivity disorder (ADHD) is a feasible target for individuals aiming to procure stimulant medication or accommodations, there is a high clinical need for accurate assessment of adult ADHD. Proven falsifiability of commonly used diagnostic instruments is therefore of concern. The present study aimed to develop a new, ADHD-specific infrequency index to aid the detection of non-credible self-report. Read More

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March 2021
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Supersensitive CeO-based nanocomposite sensor for the electrochemical detection of hydroxyl free radicals.

Authors:
Surachet Duanghathaipornsuk Dong-Shik Kim Tamara L Phares Cheng-Han Li Joerg R Jinschek Ana C Alba-Rubio

Nanoscale 2021 Mar 2. Epub 2021 Mar 2.

Department of Chemical Engineering, The University of Toledo, Toledo, OH 43606, USA.

It is well known that an excess of hydroxyl radicals (˙OH) in the human body is responsible for oxidative stress-related diseases. An understanding of the relationship between the concentration of ˙OH and those diseases could contribute to better diagnosis and prevention. Here we present a supersensitive nanosensor integrated with an electrochemical method to measure the concentration of ˙OH in vitro. Read More

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March 2021
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Human-Computer Agreement of Electrocardiogram Interpretation for Patients Referred to and Declined for Primary Percutaneous Coronary Intervention: Retrospective Data Analysis Study.

Authors:
Aleeha Iftikhar Raymond Bond Victoria Mcgilligan Stephen J Leslie Charles Knoery James Shand Adesh Ramsewak Divyesh Sharma Anne McShane Khaled Rjoob Aaron Peace

JMIR Med Inform 2021 Mar 2;9(3):e24188. Epub 2021 Mar 2.

Department of Cardiology, Altnagelvin Hospital, Western Health and Social Care Trust, Londonderry, United Kingdom.

Background: When a patient is suspected of having an acute myocardial infarction, they are accepted or declined for primary percutaneous coronary intervention partly based on clinical assessment of their 12-lead electrocardiogram (ECG) and ST-elevation myocardial infarction criteria.

Objective: We retrospectively determined the agreement rate between human (specialists called activator nurses) and computer interpretations of ECGs of patients who were declined for primary percutaneous coronary intervention.

Methods: Various features of patients who were referred for primary percutaneous coronary intervention were analyzed. Read More

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March 2021
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Clinical Techniques and Technology: Vestibular Telemetry.

Authors:
John S Phillips Jacob L Newman Stephen J Cox

Otolaryngol Head Neck Surg 2021 Mar 2:194599821993411. Epub 2021 Mar 2.

University of East Anglia, Norwich, UK.

When a patient presents to a clinician with dizziness, it can be difficult for the patient to describe their symptoms in a clear manner, and clinical examination often yields entirely normal results. Ideally, it would be favorable to measure key physiological parameters during their episodes of dizziness. From a clinical perspective, this would allow a more timely and more accurate diagnosis. Read More

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March 2021
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