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Eur J Oral Sci 2021 Feb 28:e12771. Epub 2021 Feb 28.

Institute of Dentistry, University of Turku, Turku, Finland.

We evaluated the effect of phytic acid on matrix metalloproteinase (MMP)- or cysteine cathepsin (CC)-mediated dentin degradation. Demineralized dentin beams were divided into five groups (n = 12) and treated with 1%, 2%, or 3% phytic acid or with 37% phosphoric acid. Untreated demineralized beams served as controls. Read More

Adv Genet 2021 17;107:89-120. Epub 2020 Dec 17.

Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India. Electronic address:

Natural or synthetic compounds that interfere with the bioavailability of nutrients are called antinutrients. Phytic acid (PA) is one of the major antinutrients present in the grains and acts as a chelator of micronutrients. The presence of six reactive phosphate groups in PA hinders the absorption of micronutrients in the gut of non-ruminants. Read More

Rice (N Y) 2021 Feb 27;14(1):23. Epub 2021 Feb 27.

Institute of Rural Development, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.

Background: Zn deficiency is one of the leading public health problems in the world. Staple food crop, such as rice, cannot provide enough Zn to meet the daily dietary requirement because Zn in grain would chelate with phytic acid, which resulted in low Zn bioavailability. Breeding new rice varieties with high Zn bioavailability will be an effective, economic and sustainable strategy to alleviate human Zn deficiency. Read More

Nat Struct Mol Biol 2021 Feb 25. Epub 2021 Feb 25.

Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

The striatin-interacting phosphatase and kinase (STRIPAK) complex is a large, multisubunit protein phosphatase 2A (PP2A) assembly that integrates diverse cellular signals in the Hippo pathway to regulate cell proliferation and survival. The architecture and assembly mechanism of this critical complex are poorly understood. Using cryo-EM, we determine the structure of the human STRIPAK core comprising PP2AA, PP2AC, STRN3, STRIP1, and MOB4 at 3. Read More

Sci Rep 2021 Feb 25;11(1):4684. Epub 2021 Feb 25.

School of Mechanical and Manufacturing Engineering, University of New South Wales, Sydney, NSW, 2052, Australia.

Recent discoveries of two-dimensional transitional metal based materials have emerged as an excellent candidate for fabricating nanostructured flame-retardants. Herein, we report an eco-friendly flame-retardant for flexible polyurethane foam (PUF), which is synthesised by hybridising MXene (Ti[Formula: see text]) with biomass materials including phytic acid (PA), casein, pectin, and chitosan (CH). Results show that coating PUFs with 3 layers of CH/PA/Ti[Formula: see text] via layer-by-layer approach reduces the peak heat release and total smoke release by 51. Read More