Childs Nerv Syst 2014 Mar 23;30(3):375-85. Epub 2014 Jan 23.
Paediatric Neuropsychology, The Leeds Teaching Hospitals NHS Trust, Leeds General Infirmary, Great George Street, Leeds, LS1 3EX, UK.
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J Neurosurg Pediatr 2013 Dec 27;12(6):604-14. Epub 2013 Sep 27.
Department of Pediatric Neurosurgery, Mitera Children's Hospital, Athens, Greece.
Mutism of cerebellar origin is a well-described clinical entity that complicates operations for posterior fossa tumors, especially in children. This review focuses on the current understanding of principal pathophysiological aspects and risk factors, epidemiology, clinical characteristics, treatment strategies, and outcome considerations. The PubMed database was searched using the term cerebellar mutism and relevant definitions to identify publications in the English-language literature. Read More
Cerebellum 2011 Sep;10(3):551-62
Paediatric Neurosurgery, Catholic University Medical School, Policlinic A. Gemelli, Largo Agostino Gemelli, 8, 00168, Rome, Italy.
The aim of this study is to identify possible risks factors for the occurrence of cerebellar mutism syndrome (CMS) in children with posterior cranial fossa tumours. Children diagnosed with posterior fossa tumours consecutively admitted to our institution between 2006 and 2008 were the subjects of this prospective study. Besides standard neurological and radiological evaluations, all children underwent thorough neuropsychological assessments at admission and following surgery. Read More
Acta Neurochir (Wien) 2002 May;144(5):463-73
Department of Neurosurgery, Cukurova University, School of Medicine, Adana, Turkey.
Background: Although there are some cases of cerebellar mutism in adults after posterior fossa surgery for cerebellar tumour it generally occurs in children. Reversible pathophsiology and the anatomical substrate of this syndrome still remain unclear. The predominance of cerebellar mutism in children is suggested to be related to the higher incidence of posterior fossa tumours in children. Read More
J Neurosurg Pediatr 2017 Jul 12;20(1):35-41. Epub 2017 May 12.
Departments of 1 Pediatric Neurology.
OBJECTIVE Postoperative cerebellar mutism syndrome (pCMS) occurs in 7%-50% of children after cerebellar tumor surgery. Typical features include a latent onset of 1-2 days after surgery, transient mutism, emotional lability, and a wide variety of motor and neurobehavioral abnormalities. Sequelae of this syndrome usually persist long term. Read More