Extended-spectrum β-lactamase-producing enterobacteriaceae among travelers from the Netherlands.

Authors:
Sunita Paltansing
Sunita Paltansing
Leiden University Medical Center
Netherlands
Jessica A Vlot
Jessica A Vlot
Leiden University Medical Center
Netherlands
Romy Mesman
Romy Mesman
Leiden University Medical Center
Netherlands
Alexandra T Bernards
Alexandra T Bernards
Leiden University Medical Center
Leiden | Netherlands
Leo G Visser
Leo G Visser
Leiden University Medical Center
Netherlands
Karin Ellen Veldkamp
Karin Ellen Veldkamp
University Medical Center Utrecht

Emerg Infect Dis 2013 Aug;19(8):1206-13

Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.

A prospective cohort study was performed among travelers from the Netherlands to investigate the acquisition of carbapenemase-producing Enterobacteriaceae (CP-E) and extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and associated risk factors. Questionnaires were administered and rectal swab samples were collected and tested before and after traveler return. Of 370 travelers, 32 (8.6%) were colonized with ESBL-E before trave,; 113 (30.5%) acquired an ESBL-E during travel, and 26 were still colonized 6 months after return. No CP-E were found. Independent risk factors for ESBL-E acquisition were travel to South and East Asia. Multilocus sequence typing showed extensive genetic diversity among Escherichia coli. Predominant ESBLs were CTX-M enzymes. The acquisition rate, 30.5%, of ESBL-E in travelers from the Netherlands to all destinations studied was high. Active surveillance for ESBL-E and CP-E and contact isolation precautions may be recommended at admission to medical facilities for patients who traveled to Asia during the previous 6 months.

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Source
http://dx.doi.org/10.3201/eid.1908.130257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739527PMC
August 2013
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