Eur J Cancer 2013 Sep 4;49(14):3029-40. Epub 2013 Jul 4.
Programme in Clinical Psychology, Leeds Institute of Health Sciences, Charles Thackrah Building, Clarendon Road, Leeds LS2 9LJ, UK.
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Postgrad Med 2018 Oct 10:1-7. Epub 2018 Oct 10.
d Department of Surgery , East Carolina University , Greenville , NC , USA.
In patients with type 2 diabetes secondary to excess nutrients and energy balance, relative - not absolute - insulin deficiency plays a key role in disease development and progression. Although patients with type 2 diabetes who have features of insulin resistance would usually have hyperinsulinemia, insulin therapy remains recommended by guidelines particularly when patients fail to achieve glycemic goals. This approach does not prevent complications particularly macrovascular complications. Read More
Mol Cell Biol 2018 Jun 25. Epub 2018 Jun 25.
Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, Sendai 980-8575, Japan
Cancer cells often heavily depend on the ubiquitin-proteasome system (UPS) for their growth and survival. Irrespective of their strong dependence on the proteasome activity, cancer cells, except for multiple myeloma, are mostly resistant to proteasome inhibitors. A major cause of this resistance is the "proteasome bounce-back response" mediated by NRF1, a transcription factor that coordinately activates proteasome subunit genes. Read More
J Biomol Struct Dyn 2018 02 15;36(2):443-464. Epub 2017 Feb 15.
b School of BioMedical Sciences and the Astbury Centre for Structural Molecular Biology , University of Leeds , Leeds , UK.
We report a comprehensive analysis of the numbers, lengths and amino acid compositions of transmembrane helices in 235 high-resolution structures of integral membrane proteins. The properties of 1551 transmembrane helices in the structures were compared with those obtained by analysis of the same amino acid sequences using topology prediction tools. Explanations for the 81 (5. Read More
Maedica (Buchar) 2014 Dec;9(4):356-60
Elias Universitary Hospital, Marasti Boulevard, 1 District, Bucharest, Romania.
Introduction: This study assesses the changes in human gait in the early postoperative phase of unilateral TKA, by evaluating the variability of free moment.
Materials And Method: The study group consisted of 10 patients from the Orthopedic Department of the 'Elias' University Hospital in Bucharest who undergone unilateral knee arthroplasty with the same type of posterior cruciate ligament substituting prosthesis. For the evaluation of free moment an AMTI AccuGait force platform was used. Read More
Bioresour Technol 2013 Nov 23;147:654-7. Epub 2013 Aug 23.
Department of Chemical Engineering and DST Unit on Soft Nanofabrication, Indian Institute of Technology Kanpur, 208016, India; Center for Environmental Science and Engineering, Indian Institute of Technology Kanpur, 208016, India.
When a fuel and oxidant flow in laminar contact through a micro-fluidic channel, a sharp interface appears between the two liquids, which eliminate the need of a proton exchange membrane. This principle has been used to generate potential in a membrane-less fuel cell. This study use such a cell to harvest energy of interaction between a bacteria having negative charge on its surface and a bacteriophage with positive and negative charges on its tail and head, respectively. Read More