Mol Biol Evol 2013 Sep 25;30(9):2024-34. Epub 2013 Jun 25.
Evolution of Metabolic Diversity Laboratory, Laboratorio Nacional de Genómica para la Biodiversidad (Langebio), Cinvestav-IPN, Irapuato, México.
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Expert Rev Hematol 2018 Oct;11(10):761-771
a Division of Hematology , Mayo Clinic , Rochester , MN , USA.
Introduction: Proteasome inhibitors (PIs) have been an integral part of treatment for multiple myeloma (MM) over the past decade. Many newer PIs are being evaluated in pre-clinical and clinical setting, with an aim to improve the safety, efficacy and resistance profile of this class of drugs. Ixazomib is the first oral PI with a robust efficacy and favorable safety profile in MM. Read More
Brain Inj 2018 23;32(8):1050-1055. Epub 2018 May 23.
e Medical doctor, Resident of neurosurgery, Department of Neurosurgery , Iran University of Medical Sciences , Tehran , Iran.
Introduction: Amantadine, as a dopamine receptor agonist, may stimulate and help the recovery of the nervous system after traumatic brain injury (TBI).
Methods: We performed this study as a double-blind, randomized, controlled clinical trial with target population including all patients with TBI who scored nine or lower on the Glasgow Coma Scale (GCS), admitted to our hospital between January 2013 and April 2014. The protocol included administration of the drug (placebo or amantadine) for 6 weeks and patient evaluation using the GCS and FOUR score on the first, third and seventh days after the drug was started. Read More
Gene 2018 Feb 10;642:84-94. Epub 2017 Nov 10.
Medical and Biological Computing Laboratory, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India. Electronic address:
Computational analysis of biomolecular interaction networks is now gaining a lot of importance to understand the functions of novel genes/proteins. Gene interaction (GI) network analysis and protein-protein interaction (PPI) network analysis play a major role in predicting the functionality of interacting genes or proteins and gives an insight into the functional relationships and evolutionary conservation of interactions among the genes. An interaction network is a graphical representation of gene/protein interactome, where each gene/protein is a node, and interaction between gene/protein is an edge. Read More
Hum Brain Mapp 2016 09 2;37(9):3137-52. Epub 2016 May 2.
Neuroimaging Laboratory, Department of Neurology, University of Campinas, Campinas, São Paulo, Brazil.
Mesial temporal lobe epilepsy (MTLE) with hippocampus sclerosis (HS) is associated with functional and structural alterations extending beyond the temporal regions and abnormal pattern of brain resting state networks (RSNs) connectivity. We hypothesized that the interaction of large-scale RSNs is differently affected in patients with right- and left-MTLE with HS compared to controls. We aimed to determine and characterize these alterations through the analysis of 12 RSNs, functionally parceled in 70 regions of interest (ROIs), from resting-state functional-MRIs of 99 subjects (52 controls, 26 right- and 21 left-MTLE patients with HS). Read More
Ulus Travma Acil Cerrahi Derg 2013 Mar;19(2):103-8
Department of Surgery, Government Medical College Srinagar, India.
Background: This prospective study has been conducted with the aim to assess the severity of acute pancreatitis.
Methods: The study included 350 consecutive patients with acute pancreatitis admitted over a period of five years. All these patients were subjected to detailed history and clinical examination and investigations to ascertain the diagnosis. Read More