Middle East Afr J Ophthalmol 2013 Jan-Mar;20(1):51-5
Osaka Rosai Hospital, Clinical Research Center for Occupational Sensory Organ Disability, Kita-Ku, Sakai, Japan.
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Cochrane Database Syst Rev 2015 Aug 7(8):CD008214. Epub 2015 Aug 7.
Sunderland Eye Infirmary, Queen Alexandra Road, Sunderland, UK, SR2 9HP.
Background: Postoperative vitreous cavity haemorrhage (POVCH) is a significant complication following vitrectomy for proliferative diabetic retinopathy (PDR). It delays visual recovery and can make further treatment difficult if the view of the fundus is significantly obscured. A number of interventions to reduce the incidence of POVCH have been proposed, including the perioperative use of anti-vascular endothelial growth factor (anti-VEGF). Read More
Ophthalmology 2009 Oct 21;116(10):1943-8. Epub 2009 Aug 21.
Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Objective: To evaluate the effect of preoperative intravitreal bevacizumab (IVB) injection on the rate of early (< or =4 weeks) postvitrectomy hemorrhage in patients with proliferative diabetic retinopathy (PDR).
Design: Prospective, randomized, double-masked clinical trial.
Participants: Sixty-eight eyes of 68 patients undergoing pars plana vitrectomy for management of PDR complications. Read More
Acta Ophthalmol 2010 Sep;88(6):635-40
Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Purpose: This study aimed to evaluate whether preoperative intravitreal injection of bevacizumab reduces early postoperative vitreous haemorrhage (VH) in vitrectomy for diabetic tractional retinal detachment.
Methods: We conducted a retrospective chart review of a consecutive, interventional case series. This included 29 eyes (27 patients) in the bevacizumab group and 40 eyes (37 patients) in the non-bevacizumab group. Read More
Ophthalmology 2011 Nov 2;118(11):2218-26. Epub 2011 Jul 2.
Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
Objective: To assess the effects of preoperative and intraoperative intravitreal bevacizumab (IVB) injection on the incidence of postoperative vitreous hemorrhage (VH) after vitrectomy for proliferative diabetic retinopathy (PDR).
Design: Prospective, randomized, clinical trial.
Participants: One hundred seven eyes of 91 patients undergoing pars plana vitrectomy (PPV) for the management of PDR-related complications were enrolled. Read More