Hypnosis for treatment of HIV neuropathic pain: a preliminary report.

Authors:
David Dorfman
David Dorfman
Brigham and Women's Hospital
United States
Mary Catherine George
Mary Catherine George
Icahn School of Medicine at Mount Sinai
Julie Schnur
Julie Schnur
Mount Sinai School of Medicine
David M Simpson
David M Simpson
Mount Sinai School of Medicine
United States
George Davidson
George Davidson
University of New Mexico
Guy Montgomery
Guy Montgomery
Mount Sinai School of Medicine
United States

Pain Med 2013 Jul 8;14(7):1048-56. Epub 2013 Apr 8.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York 10029-6574, USA.

Objective: Painful HIV distal sensory polyneuropathy (HIV-DSP) is the most common nervous system disorder in HIV patients. The symptoms adversely affect patients' quality of life and often diminish their capacity for independent self-care. No interventions have been shown to be consistently effective in treating the disorder. The purpose of the present study was to determine whether hypnosis could be a useful intervention in the management of painful HIV-DSP.

Method: Participants were 36 volunteers with HIV-DSP who received three weekly training sessions in self-hypnosis. Participants were followed for pain and its sequelae for 7 weeks prior to the intervention, and for 7 weeks postintervention. Participants remained on the same standard-of-care pain regimen for the entire 17 weeks of the protocol. The primary outcome measure was the Short Form McGill Pain Questionnaire cale (SFMPQ) total pain score. Other outcome measures assessed changes in affective state and quality of life.

Results: Mean SFMPQ total pain scores were reduced from 17.8 to 13.2 (F[1, 35] = 16.06, P < 0.001). The reductions were stable throughout the 7-week postintervention period. At exit, 26 out of 36 (72%) had improved pain scores. Of the 26 who improved, mean pain reduction was 44%. Improvement was found irrespective of whether or not participants were taking pain medications. There was also evidence for positive changes in measures of affect and quality of life.

Conclusion: Brief hypnosis interventions have promise as a useful and well-tolerated tool for managing painful HIV-DSP meriting further investigation.

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July 2013
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References

(Supplied by CrossRef)
Painful HIV-associated neuropathy
Phillips et al.
Pain Clin Updat 2010
Nucleoside analogue-associated peripheral neuropathy in human immunodeficiency virus infection
Simpson et al.
J AIDS 1995

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