Lab Chip 2012 Dec;12(24):5231-6
Laboratory for MEMS Applications, Department of Microsystems Engineering-IMTEK, University of Freiburg, Georges-Koehler-Allee 103, Freiburg, 79110, Germany.
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Lab Chip 2013 Aug 21;13(16):3253-60. Epub 2013 Jun 21.
Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697, USA.
Expanding upon recent applications of interfacing electricity with centrifugal microfluidic platforms, we introduce electrochemical velocimetry to monitor flow in real-time on rotating fluidic devices. Monitoring flow by electrochemical techniques requires a simple, compact setup of miniaturized electrodes that are embedded within a microfluidic channel and are connected to a peripherally-located potentiostat. On-disc flow rates, determined by electrochemical velocimetry, agreed well with theoretically expected values and with optical measurements. Read More
Lab Chip 2014 Mar;14(5):1014-22
Sensors & Biosensors Group (GSB), Department of Chemistry, Universitat Autònoma de Barcelona, Edifici Cn, Bellaterra, Catalonia, 08193, Spain.
A centrifugal microfluidic platform prototype with an integrated membrane for gas diffusion is presented for the first time. The centrifugal platform allows multiple and parallel analysis on a single disk and integrates at least ten independent microfluidic subunits, which allow both calibration and sample determination. It is constructed with a polymeric substrate material and it is designed to perform colorimetric determinations by the use of a simple miniaturized optical detection system. Read More
Chem Soc Rev 2015 Oct 2;44(17):6187-229. Epub 2015 Jun 2.
Hahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Centrifugal microfluidics has evolved into a mature technology. Several major diagnostic companies either have products on the market or are currently evaluating centrifugal microfluidics for product development. The fields of application are widespread and include clinical chemistry, immunodiagnostics and protein analysis, cell handling, molecular diagnostics, as well as food, water, and soil analysis. Read More
Lab Chip 2011 Jun 23;11(12):2023-9. Epub 2011 Mar 23.
Área de Mecánica de Fluidos, Departamento de Ingeniería Aeroespacial y Mecánica de Fluidos, Universidad de Sevilla, Avda. de los Descubrimientos s/n, 41092 Sevilla, Spain.
A new regime of operation of PDMS-based flow-focusing microfluidic devices is presented. We show that monodisperse microbubbles with diameters below one-tenth of the channel width (here w = 50 μm) can be produced in low viscosity liquids thanks to a strong pressure gradient in the entrance region of the channel. In this new regime bubbles are generated at the tip of a long and stable gas ligament whose diameter, which can be varied by tuning appropriately the gas and liquid flow rates, is substantially smaller than the channel width. Read More