BMC Bioinformatics 2012 11;13 Suppl 15:S7. Epub 2012 Sep 11.
Department of Academic and Institutional Resources and Technology, University of North Texas Health Science Center, Fort Worth, USA.
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Indian J Community Med 2017 Oct-Dec;42(4):248-249
State Correspondent, The Statesman and Alumni of HP Agriculture University, Palampur, Himachal Pradesh, India.
Am J Clin Pathol 2016 Jul 27;146(1):78-85. Epub 2016 Jun 27.
From the National Amyloidosis Centre, University College London Medical School, Royal Free Hospital Campus, London, United Kingdom
Objectives: Measurement of serum free light chains (FLCs) is critical in diagnosis, prognosis, and monitoring treatment responses in light chain (AL) amyloidosis. We compare the Freelite assay (polyclonal antibodies to hidden light chain epitopes), which is the current gold standard, with a new assay: a mixture of monoclonal antibodies to light chain epitopes (N Latex).
Methods: We collected 240 serum samples from 94 consecutive patients with newly diagnosed AL amyloidosis (at least three serial serum samples during the first 6 months) analyzed at the National Amyloidosis Centre, London, from January 2011 to April 2012. Read More
Indian J Hum Genet 2013 Jan;19(1):84-6
Department of Medical Genetics, Sarem Cell Research Center, Sarem Women Hospital, Tehran, Iran.
Fanconi-Bickel syndrome is an extremely rare hereditary metabolic disease, characterized by hepatomegaly due to glycogen storage, refractory hypophosphatemic rickets, marked growth retardation and proximal renal tubular acidosis. Recurrent bone fractures are one of the hallmark findings. It is a single gene disorder; the responsible gene belongs to the facilitative glucose transporters 2 (GLUT2) family gene or (SLC2A2) mapped to the q26. Read More
Ann Transl Med 2013 Jul;1(2):21
1 Department of Pathology, 2 Department of Thoracic Surgery, Abderrahmen Mami Hospital, 2083 Ariana, Tunisia.
Dyshormonogenetic goiter is a rare cause of congenital hypothyroidism occurring due to a lack of enzymes necessary for the synthesis of thyroid hormones. It is morphologically characterized by architectural and cellular pleomorphism that may mimic thyroid malignancy and cause difficulties in differential diagnosis. We report a new case occurring in a 37-year-old male with history of hypothyroidism since the age of 6 years treated by L-thyroxin. Read More
J Infect Dis 2013 Oct 6;208(7):1113-22. Epub 2013 Jun 6.
Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston MA 02215, USA.
Background: Human immunodeficiency virus type 1 (HIV-1) infection is associated with a massive depletion of intestinal CD4(+) T cells that is only partially reversed by combination antiretroviral therapy (cART). Here, we assessed the ability of nucleoside reverse-transcriptase inhibitor/nonnucleoside reverse-transcriptase inhibitor treatment to restore the CD4(+) T-cell populations in the intestine of South African patients with AIDS.
Methods: Thirty-eight patients with advanced HIV-1 infection who had chronic diarrhea (duration, >4 weeks) and/or unintentional weight loss (>10% decrease from baseline) of uncertain etiology were enrolled. Read More