Lens and retina regeneration: new perspectives from model organisms.

Biochem J 2012 Nov;447(3):321-34

Department of Zoology, Miami University, Oxford, OH 45056, USA.

Comparative studies of lens and retina regeneration have been conducted within a wide variety of animals over the last 100 years. Although amphibians, fish, birds and mammals have all been noted to possess lens- or retina-regenerative properties at specific developmental stages, lens or retina regeneration in adult animals is limited to lower vertebrates. The present review covers the newest perspectives on lens and retina regeneration from these different model organisms with a focus on future trends in regeneration research.

Download full-text PDF

Source
http://biochemj.org/lookup/doi/10.1042/BJ20120813
Publisher Site
http://dx.doi.org/10.1042/BJ20120813DOI Listing
November 2012
54 Reads

Publication Analysis

Top Keywords

retina regeneration
16
lens retina
16
model organisms
8
regeneration
5
newest perspectives
4
birds mammals
4
lens
4
mammals possess
4
covers newest
4
perspectives lens
4
100 years amphibians
4
regeneration model
4
amphibians fish
4
possess lens-
4
fish birds
4
review covers
4
vertebrates review
4
specific developmental
4
lower vertebrates
4
developmental stages
4

References

(Supplied by CrossRef)
Entwicklungsphyiologische Studien. I. Die Regeneration der Urodelenlinse
Wolff et al.
Wilhelm Roux’ Arch. Entwicklungsmech. Org. 1895
Sulla rigenerazione parziale deell’occhio nei tritoni: isogenesi esvilluppo-Studio seprimentale
Colluci et al.
Mem. Accad. Sci. Ist. Bologna, Cl. Sci. Fis. 1891
Fibre cell organization in crystalline lenses
Kuszak et al.
Exp. Eye Res. 2004
Morphology and organization of posterior fiber ends during migration
Al-Ghoul et al.
Mol. Vision 2003
Retina and lens regeneration in anuran amphibians
Filoni et al.
Semin. Cell Dev. Biol. 2009

Similar Publications