Pediatr Dermatol 2013 May-Jun;30(3):e8-e11. Epub 2012 Sep 20.
Department of Dermatology, Indiana University, Indianapolis, IN 46202, USA.
Granular cell tumors are uncommon neoplasms postulated to derive from Schwann cells. They are histologically unique and exhibit S-100 positivity. Pediatric occurrences are uncommon, and familial cases are rare. A limited number of familial granular cell tumors have been reported. We describe two siblings with granular cell tumors and review the relevant literature.