Centrifugal microfluidics for cell analysis.

Authors:
Robert Burger
Robert Burger
University of California
United States
Daniel Kirby
Daniel Kirby
School of Life and Health Sciences
United Kingdom
Macdara Glynn
Macdara Glynn
Dublin City University
Ireland
Charles Nwankire
Charles Nwankire
Biomedical Diagnostics Institute
Jonathan Siegrist
Jonathan Siegrist
University of California
United States
David Kinahan
David Kinahan
Biomedical Diagnostics Institute
Gerson Aguirre
Gerson Aguirre
Dublin City University
Ireland

Curr Opin Chem Biol 2012 Aug 9;16(3-4):409-14. Epub 2012 Jul 9.

Biomedical Diagnostics Institute, National Centre for Sensor Research, School of Physical Sciences, Dublin City University, Ireland.

Over the past two decades, centrifugal microfluidic systems have successfully demonstrated their capability for robust, high-performance liquid handling to enable modular, multi-purpose lab-on-a-chip platforms for a wide range of life-science applications. Beyond the handling of homogeneous liquids, the unique, rotationally controlled centrifugal actuation has proven to be specifically advantageous for performing cell and particle handling and assays. In this review we discuss technologies to implement two important steps for cell handling, namely separation and capturing/counting.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cbpa.2012.06.002DOI Listing

Still can't find the full text of the article?

We can help you send a request to the authors directly.
August 2012
35 Reads
8 Citations
6.810 Impact Factor

Publication Analysis

Top Keywords

unique rotationally
4
liquids unique
4
rotationally controlled
4
controlled centrifugal
4
actuation proven
4
centrifugal actuation
4
homogeneous liquids
4
handling homogeneous
4
lab-on-a-chip platforms
4
multi-purpose lab-on-a-chip
4
platforms wide
4
wide range
4
applications handling
4
range life-science
4
proven advantageous
4
advantageous performing
4
implement steps
4
technologies implement
4
steps cell
4
cell handling
4

Similar Publications