Clinical and histopathological features of orbital granular cell tumor: case report.

Arq Bras Oftalmol 2012 Mar-Apr;75(2):137-9

Department of Ophthalmology and Pathology, Henry C. Witelson Ocular Pathology Laboratory & McGill University Health Centre, Montreal, QC, Canada.

A 53 year-old woman presented with a slowly progressive, painless proptosis OS. Computed tomography disclosed a round, homogeneous, well-delimited lesion in the inferior-temporal orbit. The tumor was composed of round cells with eosinophilic granular cytoplasm. Some of the cells had larger eosinophilic granules surrounded by a clear halo; known as pustulo-ovoid bodies of Milian or Bangle bodies. The diagnosis of a granular cell tumor was then established and confirmed by immunohistochemistry. Granular cell tumors are uncommon benign soft tissue neoplasms that have a predilection for the head and neck region. Awareness of the typical histopathological features is crucial for the correct diagnosis.

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http://dx.doi.org/10.1590/s0004-27492012000200014DOI Listing
February 2013

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