Can noninvasive brain stimulation enhance cognition in neuropsychiatric disorders?

Authors:
Asli Demirtas-Tatlidede, MD, PhD
Asli Demirtas-Tatlidede, MD, PhD
Bahcesehir University
Professor of Neurology
Dementia, Behavioral Neurology, Movement Disorders
Istanbul, Choose one... | Turkey

Neuropharmacology 2013 Jan 28;64:566-78. Epub 2012 Jun 28.

Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey.

Cognitive impairment is a core symptom of many neuropsychiatric diseases and a key contributor to the patient's quality of life. However, an effective therapeutic strategy has yet to be developed. Noninvasive brain stimulation techniques, namely transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), are promising techniques that are under investigation for a variety of otherwise treatment-resistant neuropsychiatric diseases. Notably, these tools can induce alterations in neural networks subserving cognitive operations and thus may provide a means for cognitive restoration. The purpose of this article is to review the available evidence concerning cognitive enhancing properties of noninvasive brain stimulation in neuropsychiatry. We specifically focus on major depression, Alzheimer's disease, schizophrenia, autism and attention deficit hyperactivity disorder (ADHD), where cognitive dysfunction is a major symptom and some studies have been completed with promising results. We provide a critical assessment of the available research and suggestions to guide future efforts. This article is part of a Special Issue entitled 'Cognitive Enhancers'.

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Source
http://dx.doi.org/10.1016/j.neuropharm.2012.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725288PMC

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January 2013
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