Search Our Scientific Publications & Authors

Ann Thorac Surg 2021 Mar 1. Epub 2021 Mar 1.

Department of Cardiovascular Surgery. Electronic address:

Background: Delayed sternal closure (DSC) is a management strategy for hemodynamic instability and severe coagulopathy after complex congenital heart surgery. We hypothesized that DSC results in better outcomes than perioperative sternal reopening.

Methods: We reviewed patients <18 years old undergoing cardiac surgery 2007-2017 at our institution. Read More

Mol Genet Genomic Med 2021 Mar 4:e1651. Epub 2021 Mar 4.

Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Central South University, Changsha, China.

Background: Leigh syndrome, the most common mitochondrial syndrome in pediatrics, has diverse clinical manifestations and is genetically heterogeneous. Pathogenic mutations in more than 75 genes of two genomes (mitochondrial and nuclear) have been identified. PDHA1 encoding the E1 alpha subunit is an X-chromosome gene whose mutations cause pyruvate dehydrogenase complex deficiency. Read More

Pediatr Crit Care Med 2021 Mar 5. Epub 2021 Mar 5.

Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA. Division of Critical Care Medicine, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA. Department of Anaesthesia, Harvard Medical School, Boston, MA. Department of Cardiology, Boston Children's Hospital, Boston, MA. Department of Pediatrics, Harvard Medical School, Boston, MA. Computational Health Informatics Program, Boston Children's Hospital, Boston, MA.

Objectives: Anticoagulation plays a key role in the management of children supported with extracorporeal membrane oxygenation. However, the ideal strategy for monitoring anticoagulation remains unclear. Our objective was to evaluate the utility of laboratory measures of anticoagulation in pediatric extracorporeal membrane oxygenation. Read More

Perfusion 2021 Mar 3:267659121998944. Epub 2021 Mar 3.

Department of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.

Background: Extracorporeal membrane oxygenation (ECMO) is a rescue procedure used for cardiac and pulmonary dysfunction. Patients on ECMO often require blood transfusions to maintain oxygen delivery and recover from bleeding complications. Goals of the current study were to determine transfusion requirements while on ECMO, and incidence and transfusion requirements for bleeding complications. Read More

Pediatr Crit Care Med 2021 Mar;22(3):334-336

Department of Child Health, University of Arizona College of Medicine, Phoenix, AZ.