Clin Biochem 2012 Jul 26;45(10-11):842-4. Epub 2012 Apr 26.
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester MN 55905, USA.
Objectives: In an attempt to reduce false positive results and improve turnaround time, we investigated the BD Rapid Serum Tube as an alternate sample type to lithium heparin plasma for Roche Troponin T analysis on the Roche Cobas e411 analyzer.
Design And Methods: BD Plasma Separator Tubes (PST) and Rapid Serum Tubes (RST) were collected in tandem from Emergency Department patients who had clinical orders for Troponin T over a 1 month period.
Results: RST and PST samples yielded analytically and clinically concordant Troponin T results on the Roche Cobas e411. Rare false positive results in lithium heparin samples were not observed with rapid clot serum tubes.
Conclusions: RST samples are appropriate for stat Troponin T analysis, and appear to reduce the incidence of rare false positive Troponin T results obtained with lithium heparin samples.