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Comput Med Imaging Graph 2021 Mar 14;90:101898. Epub 2021 Mar 14.

Department of Radiology and Imaging, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong, Hong Kong.

The hyperdense middle cerebral artery sign (HMCAS) representing a thromboembolus has been declared as a vital CT finding for intravascular thrombus in the diagnosis of acute ischemia stroke. Early recognition of HMCAS can assist in patient triage and subsequent thrombolysis or thrombectomy treatment. A total of 624 annotated head non-contrast-enhanced CT (NCCT) image scans were retrospectively collected from multiple public hospitals in Hong Kong. Read More

Pathol Res Pract 2021 Mar 24;221:153415. Epub 2021 Mar 24.

Anatomical Sciences Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran. Electronic address:

Background: Female sex hormones are protective factors against many neurological disorders such as brain ischemia. Heat shock protein like HSP27 is activated after tissue injury. The main purpose of the present study is to determine the effect of a combined estrogen / progesterone cocktail on the morphology of astrocytes, neurons and Hsp27 phosphorylation after cerebral ischemia. Read More

Ann Thorac Surg 2021 Apr 12. Epub 2021 Apr 12.

Division of Cardiothoracic Surgery, Department of Surgery, Westchester Medical Center, New York Medical College, Valhalla, NY.

Background: This study reviews the outcomes of our reoperative total arch repair (TAR) technique using a trifurcated graft and selective antegrade cerebral perfusion (SACP).

Methods: Fifty patients underwent reoperative TAR from January 2005 to September 2020, with either a one-stage (N=9), or two-stage repair (N=41). The two-stage technique includes minimal dissection of the mediastinal structures, an arch-first technique using a trifurcated graft, and construction of a classical elephant trunk via a partial transverse incision distally in the old-graft or in the aorta just distal to the old graft. Read More

Anesthesiology 2021 Apr 15. Epub 2021 Apr 15.

Background: With increasing use of tranexamic acid in total hip and knee arthroplasties, safety concerns remain. Using national claims data, this study examined tranexamic acid use in patients with preexisting comorbidities. The hypothesis was that tranexamic acid use is not associated with increased complication risk in hip and knee arthroplasty patients with comorbidities. Read More

Neurol Neurochir Pol 2021 Apr 15. Epub 2021 Apr 15.

Department of Neurology, Institute of Medical Sciences, Medical College of Rzeszow University, Poland.

Introduction: The aim of this study was to report the course and outcome of SARS-CoV-2 infection in multiple sclerosis (MS) patients treated with disease-modifying therapies (DMTs) in Poland. A major concern for neurologists worldwide is the course and outcome of SARS-CoV-2 infection in patients with MS treated with different DMTs. Although initial studies do not suggest an unfavourable course of infection in this group of patients, the data is limited. Read More