Familial Lund frontotemporal dementia caused by C9ORF72 hexanucleotide expansion.

Neurobiol Aging 2012 Aug 6;33(8):1850.e13-6. Epub 2012 Apr 6.

Department of Pathology, Lund University, Regional Laboratories Region Skåne, Lund, Sweden.

Frontotemporal dementia (FTD) as an important clinical entity was rediscovered in Lund and Manchester in the early 1990s. Here we show that the large Lund pedigree with behavioral variant of frontotemporal dementia previously described with this disorder has an expansion in the recently described C9ORF72 locus on chromosome 9.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2012.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562220PMC
August 2012
6 Reads

Publication Analysis

Top Keywords

frontotemporal dementia
12
rediscovered lund
4
lund manchester
4
disorder expansion
4
entity rediscovered
4
described c9orf72
4
clinical entity
4
expansion described
4
described disorder
4
early 1990s
4
lund pedigree
4
variant frontotemporal
4
pedigree behavioral
4
large lund
4
1990s large
4
behavioral variant
4
dementia described
4
manchester early
4
ftd clinical
4
dementia caused
4

Similar Publications