Informatics and data quality at collaborative multicenter Breast and Colon Cancer Family Registries.

J Am Med Inform Assoc 2012 Jun 9;19(e1):e125-8. Epub 2012 Feb 9.

Clinical Research Informatics, Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

Quality control and harmonization of data is a vital and challenging undertaking for any successful data coordination center and a responsibility shared between the multiple sites that produce, integrate, and utilize the data. Here we describe a coordinated effort between scientists and data managers in the Cancer Family Registries to implement a data governance infrastructure consisting of both organizational and technical solutions. The technical solution uses a rule-based validation system that facilitates error detection and correction for data centers submitting data to a central informatics database. Validation rules comprise both standard checks on allowable values and a crosscheck of related database elements for logical and scientific consistency. Evaluation over a 2-year timeframe showed a significant decrease in the number of errors in the database and a concurrent increase in data consistency and accuracy.

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http://dx.doi.org/10.1136/amiajnl-2011-000546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392863PMC
June 2012
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References

(Supplied by CrossRef)

John et al.
Breast cancer research : BCR 2004

Cancer Epidemiology Biomarkers & Prevention 2007

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