The safety and diagnostic value of frame-based and CT-guided stereotactic brain biopsy technique.

Authors:
Prof Tayfun Hakan, MD
Prof Tayfun Hakan, MD
Fatih Sultan Mehmet Training and Research Hospital
Prof. Dr.
Ataşehir, İstanbul | Turkey

Turk Neurosurg 2011 ;21(4):582-90

Samsun Education and Research Hospital, Department of Neurosurgery, Samsun, Turkey.

Aim: Histopathological diagnosis is always necessary to make an effective treatment plan for intracranial mass lesions. This study aimed to evaluate the diagnostic efficacy, and associated mortality and morbidity of CT-guided stereotactic biopsy procedures in a large number of patients with intracranial lesions.

Material And Methods: A total of 290 cases undergoing CT-guided stereotactic biopsy for intracranial lesions were included in this retrospective study. Clinical, radiological and histological data in patient records were examined.

Results: The mean age of the patients was 46.6 years (range: 2-82 y). Pediatric patients comprised 6.3% (n=13) of the total population. Examination of paraffin embedded histological preparations revealed a tumoral mass in 240 (82.8%), a non-tumoral mass in 37 (12.8%), and non-definable lesions in 13 (4.5%). Therefore, the diagnostic value in this series was 95.5%. Postoperative mortality rate was 0.8% (n=2). When histopathological diagnoses made after biopsy and surgical resection were compared in 42 patients with available data, a complete or partial agreement was present in 90.5%.

Conclusion: Our findings support that frame based-stereotactic biopsy is a safe and valuable technique that allows the neurosurgeon to obtain tissue samples for histopathological diagnosis of intracranial mass lesions in almost any region.

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Source
http://dx.doi.org/10.5137/1019-5149.JTN .4656-11.1DOI Listing
April 2012
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