Influenza vaccination and cardiovascular morbidity and mortality: analysis of 292,383 patients.

J Cardiovasc Pharmacol Ther 2012 Sep 14;17(3):277-83. Epub 2011 Dec 14.

Children's Hospital of Wisconsin/Medical College of Wisconsin Affiliated Hospitals, Wauwatosa, WI 53226, USA.

Studies have documented an association between influenza vaccination and risk reduction in myocardial infarction, all-cause mortality, and major adverse cardiac events. This meta-analysis pooled data from 5 trials with a total of 292 383 patients. Influenza vaccination was found to be associated with significant reductions in myocardial infarction, all-cause mortality, and major adverse cardiac events. The risk reduction afforded by vaccination and the lack of major adverse events related to the influenza vaccination makes it particularly important to vaccinate those with a known cardiovascular disease or those at high risk of developing cardiovascular disease.

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http://dx.doi.org/10.1177/1074248411429965DOI Listing
September 2012
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