Cardiac disease in methylmalonic acidemia.

Authors:
Carlos E Prada
Carlos E Prada
Cincinnati Children's Hospital Medical Center
United States
Edwin P Kirk
Edwin P Kirk
University of New South Wales
Australia
Maxwell Hopp
Maxwell Hopp
Griffith Base Hospital
Griffith | Australia
Owen Jones
Owen Jones
University of Manchester
United Kingdom
Nancy D Leslie
Nancy D Leslie
Cincinnati Children's Hospital Medical Center

J Pediatr 2011 Nov 23;159(5):862-4. Epub 2011 Jul 23.

Division of Human Genetics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Methylmalonic acidemia (MMA) is a heterogeneous disorder, with onset from infancy to adulthood and varying degrees of organ involvement and severity. Cardiac disease is a known lethal complication of other organic acidemias, but has not been associated with MMA. We identified 3 patients with MMA and cardiac disease.

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http://dx.doi.org/10.1016/j.jpeds.2011.06.005DOI Listing
November 2011
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