HTLV infection among foreign pregnant women living in Spain.

Authors:
Ana Trevino
Ana Trevino
University of Kansas Medical Center
United States
Rafael Benito
Rafael Benito
Hospital Carlos III
Spain
Estrella Caballero
Estrella Caballero
Hospital Carlos III
Spain
Jose Manuel Ramos
Jose Manuel Ramos
Gambo General Rural Hospital
Patricia Parra
Patricia Parra
Hospital Carlos III
Spain
Lourdes Roc
Lourdes Roc
Hospital Miguel Servet
Zaragoza | Spain
Jose Maria Eiros
Jose Maria Eiros
Hospital Clínico Universitario de Valladolid
Spain
Antonio Aguilera
Antonio Aguilera
Hospital Carlos III
Spain

J Clin Virol 2011 Oct 22;52(2):119-22. Epub 2011 Jul 22.

Infectious Diseases Department, Hospital Carlos III, Calle Sinesio Delgado 10, Madrid, Spain.

Background: The overall seroprevalence of HTLV infection among pregnant women in Spain is below 0.02% and accordingly universal antenatal screening is not recommended. However, as the number of immigrants has significantly increased during the last decade, this population might warrant specific considerations.

Objective: To evaluate the seroprevalence of HTLV infection among immigrant pregnant women living in Spain.

Methods: From January 2009 to December 2010 a cross-sectional study was carried out in all foreign pregnant women attended at 14 Spanish clinics. All were tested for HTLV antibodies using a commercial enzyme-immunoassay, being reactive samples confirmed by Western blot or PCR.

Results: A total of 3337 foreign pregnant women were examined. Their origin was as follows: Latin America 1579 (47%), North Africa 507 (16%), East Europe 606 (18%), Sub-Saharan Africa 316 (9%), North America and West Europe 116 (3.5%) and Asia and Australia 163 (5%). A total of 7 samples were confirmed as HTLV positive, of which 6 were HTLV-1 and 1 HTLV-2. HTLV-1 infection was found in 5 women coming from Latin America and 1 from Morocco. The only woman with HTLV-2 came from Ghana. The overall HTLV seroprevalence was 0.2%, being 0.3% among Latin Americans and 0.2% among Africans. It was absent among women coming from other regions.

Conclusions: The seroprevalence of HTLV infection among foreign pregnant women in Spain is 0.2%, being all cases found in immigrants from Latin America and Africa. Given the benefit of preventing vertical transmission, antenatal screening should be recommended in pregnant women coming from these regions.

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Source
http://dx.doi.org/10.1016/j.jcv.2011.06.010DOI Listing
October 2011
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