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Mol Neurobiol 2021 Apr 15. Epub 2021 Apr 15.

Complex Disease Genomics and Precision Medicine Laboratory, Department of Human Genetics and Molecular Medicine, Central University of Punjab, Bathinda, Punjab, 151001, India.

Epilepsy and migraine are both episodic disorders and share clinical as well as pathophysiological mechanisms. The prevalence of epilepsy in migraine patients is generally higher than normal as compared to general population and vice versa. Various environmental risk factors and genetic factors have been reported to be associated with susceptibility of these comorbid diseases. Read More

Radiol Case Rep 2021 Jun 28;16(6):1276-1279. Epub 2021 Mar 28.

Division of Child Neurology, Indiana University School of Medicine, Indianapolis, IN.

Pathogenic gene variants are associated with a spectrum of disorders including migraine with or without hemiplegia, ataxia, epilepsy, and developmental disability. We present a case of a pathogenic variant (c.4046G>A, p. Read More

Seizure 2021 Mar 31;88:87-94. Epub 2021 Mar 31.

Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey; Neuroscience Department, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey. Electronic address:

Objective: The coexistence of epilepsy in familial hemiplegic migraine (FHM) has not been reviewed systematically. We investigated the associations of epilepsy in patients with FHM with CACNA1A, ATP1A2, SCN1A or PRRT2 mutations along with clinical and genetic data.

Materials And Methods: We performed a search in the PubMed bibliographic database and the Cochrane Library was screened for eligible studies, from April 1997 to December 2020. Read More

J Clin Med 2021 Mar 25;10(7). Epub 2021 Mar 25.

Newcastle-Upon-Tyne Hospitals NHS Foundation Trust, Newcastle-Upon-Tyne NE1 4LP, UK.

Background: The 2019 novel coronavirus pandemic has generated concern from stroke specialist centres across the globe. Reductions in stroke admissions have been reported, despite many expecting an increase due to the pro-thrombotic nature of 2019 novel coronavirus.

Aims: To assess the impact of the pandemic and subsequent lockdown on stroke admissions and transient ischaemic attack referrals at the Royal Victoria Infirmary, Newcastle-Upon-Tyne, and additionally on patient behaviours affecting modifiable risk factors or perspectives related to accessing healthcare. Read More

Children (Basel) 2021 Mar 17;8(3). Epub 2021 Mar 17.

Division of Pain Medicine, Department of Anesthesiology, Boston Children's Hospital, Boston, MA 02115, USA.

Migraine headache is a common cause of pain and disability in children and adolescents and is a major contributor to frequently missed school days and limitations in activities. Of children and adolescents with migraine headache, approximately one-third have migraine with aura (MA). MA is often considered to be similar to migraine without aura (MO), and thus, many studies do not stratify patients based on the presence of aura. Read More