Indian J Med Res 2010 Jul;132:4-8
Mangla Hospital, Bijnor, UP.
J Public Health Manag Pract 2021 Aug 2. Epub 2021 Aug 2.
Tuberculosis Control Program, Public Health-Seattle & King County, Seattle, Washington (Mss Gustavson and Gardner Toren and Dr Narita); and Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, Washington (Dr Narita).
From October 15, 2019, to June 12, 2020, Public Health-Seattle & King County conducted phone outreach to individuals referred to the public health department by civil surgeons. The objective was to explore common barriers and facilitators to treatment of latent tuberculosis infection (LTBI) among this population. Civil surgeons are mandated to report cases of LTBI to the state or local health department. Read More
J Int AIDS Soc 2021 Aug;24(8):e25775
ISGlobal, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Introduction: AIDS-mortality remains unacceptably high in sub-Saharan Africa, largely driven by advanced HIV disease (AHD). We nested a study in an existing tuberculosis (TB) contact-tracing intervention (Xpatial-TB). The aim was to assess the burden of AHD among high-risk people living with HIV (PLHIV) identified and to evaluate the provision of the WHO-recommended package of care to this population. Read More
J Exp Med 2021 Oct 4;218(10). Epub 2021 Aug 4.
Tuberculosis Center, Shanghai Emerging and Re-emerging Infectious Disease Institute, Fudan University, Shanghai, China.
Host resistance to Mycobacterium tuberculosis (Mtb) infection requires the activities of multiple leukocyte subsets, yet the roles of the different innate effector cells during tuberculosis are incompletely understood. Here we uncover an unexpected association between eosinophils and Mtb infection. In humans, eosinophils are decreased in the blood but enriched in resected human tuberculosis lung lesions and autopsy granulomas. Read More
mSphere 2021 Aug 4:e0054921. Epub 2021 Aug 4.
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Autophagy is a fundamental cellular process that has important roles in innate and adaptive immunity against a broad range of microbes. Many pathogenic microbes have evolved mechanisms to evade or exploit autophagy. It has been previously demonstrated that induction of autophagy can suppress the intracellular survival of mycobacteria, and several PE_PGRS family proteins of Mycobacterium tuberculosis have been proposed to act as inhibitors of autophagy to promote mycobacterial survival. Read More
BMJ Glob Health 2021 08;6(8)
The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia
Introduction: The aim of this mixed-method study was to determine the extent and determinants of inappropriate dispensing of antibiotics by licensed private drug retail outlets in Indonesia.Methods: Standardised patients (SPs) made a total of 495 visits to 166 drug outlets (community pharmacies and drug stores) between July and August 2019. The SPs presented three clinical cases to drug outlet staff: parent of a child at home with diarrhoea; an adult with presumptive tuberculosis (TB); and an adult with upper respiratory tract infection (URTI). Read More