Cancer 2010 Jul;116(13):3285-93
Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
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J Cachexia Sarcopenia Muscle 2018 Oct 11. Epub 2018 Oct 11.
Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Lodz, Poland.
Background: The 'placebo effect' and 'nocebo effect' are phenomena whereby beneficial (placebo) or adverse (nocebo) effects result from the expectation that an inert substance will relieve or cause a particular symptom. These terms are often inappropriately applied to effects experienced on drug therapy. Quantifying the magnitude of placebo and nocebo effects in clinical trials is problematic because it requires a 'no treatment' arm. Read More
Org Lett 2018 05 8;20(10):2925-2928. Epub 2018 May 8.
Indian Institute of Technology Kanpur , 208016 , Kanpur , Uttar Pradesh , India.
An expeditious synthetic route to access structurally diverse 1,4,5,6-tetrahydropyrimidines via domino ring-opening cyclization of activated aziridines with α-acidic isocyanides has been established. The transformation proceeds via Lewis acid mediated S2-type ring opening of activated aziridines with α-carbanion of the isocyanides followed by a concomitant 6- endo- dig cyclization in a domino fashion to furnish the 1,4,5,6-tetrahydropyrimidine derivatives in excellent yields (up to 84%) and also in diastereo- and enantiomerically pure form (dr >99:1, ee >99%). Read More
Cell Death Dis 2017 03 23;8(3):e2692. Epub 2017 Mar 23.
Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA.
Crit Rev Anal Chem 2016 Nov 23;46(6):482-9. Epub 2016 Feb 23.
a Department of Chemistry, Government Degree College , Rajampeta, Kadapa Dist., Andhra Pradesh , India.
Modafinil is a synthetic molecule used for the treatment of narcolepsy. Narcolepsy is a neurological disorder, due to which people experience frequent excessive daytime sleepiness (EDS). Nevertheless, there are some concerns about modafnil quality control. Read More
Sci Rep 2015 Jul 10;5:12035. Epub 2015 Jul 10.
Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati-517502, Andhra Pradesh, India.
Integrating cancer genes and markers with experimental evidence might provide valuable information for the further investigation of crosstalk between tumor genes and markers in cancer biology. To achieve this objective, we developed a database known as the Cancer Gene Marker Database (CGMD), which integrates data on tumor genes and markers based on experimental evidence. The major goal of CGMD is to provide the following: 1) current systematic treatment approaches and recent advances in different cancer treatments; 2) the aggregation of different genes and markers by their molecular characteristics and pathway associations; and 3) free access to the data compiled by CGMD at http://cgmd. Read More