Br J Nutr 2010 Oct 21;104(7):965-71. Epub 2010 May 21.
Centre of System Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai 200093, People's Republic of China.
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Osteoporos Int 2011 Feb 23;22(2):703-9. Epub 2010 Apr 23.
Center of System Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai, 200093, People's Republic of China.
Unlabelled: The purpose of this study is to investigate the dose-dependent effects of SWH on bone properties and the mechanism involved in mediating the osteoprotective actions of SWH. The results indicated that SWH could improve bone properties by inhibiting the process of bone resorption and stimulating the process of bone formation.
Introduction: Our previous study showed that Sambucus williamsii HANCE (SWH) improved trabecular bone mass and cortical bone strength in ovariectomized (OVX) rats. Read More
Mol Cell Endocrinol 2017 Jan 21;439:369-378. Epub 2016 Sep 21.
Department of Orthopaedic Surgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi 530021, China; Research Centre for Regenerative Medicine, Guangxi Medical University, Guangxi 530021, China; School of Pathology and Laboratory Medicine, The University of Western Australia, Perth, WA 6009, Australia. Electronic address:
Excessive bone resorption by osteoclasts plays an important role in osteoporosis. Bone loss occurs in ovariectomised (OVX) mice in a similar manner to that in humans, so this model is suitable for evaluating potential new therapies for osteoporosis. Neohesperidin (NE) is a flavonoid compound isolated from citrus fruits. Read More
Phytomedicine 2016 Apr 15;23(4):417-28. Epub 2016 Feb 15.
Department of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan. Electronic address:
Background: Osteoporosis is a bone pathology leading to increased fracture risk and challenging the quality of life. As current treatments can exhibit deleterious side effects, the use of phyto-compounds with therapeutic and preventive activities against orthopaedic related problems represents a promising alternative.
Purpose: We investigated the effect of aloin, an anthrocyclic compound, on inhibition of osteoclastogenesis using receptor of the nuclear factor κB (NF-κB) ligand (RANKL)-induced RAW264. Read More
Int J Environ Res Public Health 2015 Oct 28;12(11):13779-93. Epub 2015 Oct 28.
Department of Physiology, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.
Honeybush tea, a sweet tasting caffeine-free tea that is indigenous to South Africa, is rich in bioactive compounds that may have beneficial health effects. Bone remodeling is a physiological process that involves the synthesis of bone matrix by osteoblasts and resorption of bone by osteoclasts. When resorption exceeds formation, bone remodeling can be disrupted resulting in bone diseases such as osteoporosis. Read More