Cutaneous collagenous vasculopathy with generalized telangiectasia in two female patients.

Authors:
Alfonso Perez
Alfonso Perez
Takeda Development Center Americas
Alistair Robson
Alistair Robson
St John's Institute of Dermatology
United Kingdom
Richard W Groves
Richard W Groves
St Thomas' Hospital
United Kingdom
Catherine M Stefanato
Catherine M Stefanato
St John's Institute of Dermatology
United Kingdom

J Am Acad Dermatol 2010 Nov 6;63(5):882-5. Epub 2010 May 6.

St John's Institute of Dermatology, St Thomas' Hospital, London, UK.

Cutaneous collagenous vasculopathy is characterized by generalized cutaneous telangiectasia and unique microscopic and ultrastructural vascular changes, consisting of marked collagen deposition within the vascular walls of the post-capillary venules in the superficial dermis. There are only 4 previous cases described in the medical literature, all in males, mostly middle-aged. We have recently seen two female patients with clinical and histopathologic features diagnostic of cutaneous collagenous vasculopathy, indicating that it is not restricted to males. As cutaneous collagenous vasculopathy can be clinically indistinguishable from generalized essential telangiectasia, and histopathologic studies are rarely performed for this condition, it is likely that cutaneous collagenous vasculopathy frequently passes unrecognized, but it may be more common than previously thought.

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http://dx.doi.org/10.1016/j.jaad.2009.06.045DOI Listing

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November 2010
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