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    Myth and reality of pragmatic trials.

    Psychiatr Danub 2010 Mar;22(1):2-3

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    Clinical trials and tribulations: implementation processes in schizophrenia research outcome.
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    Wurzweiler School of Social Work, Yeshiva University, New York 10033-3299, USA.
    This article focuses on an area in clinical drug trials for new antipsychotic medications for the treatment of schizophrenia which has not received sufficient attention in the literature: the day-to-day implementation tasks performed by research staff which have potential effects on study results. Implementation tasks are viewed as dynamic processes involving interactions among research and nonresearch staff, patients, families, and pharmaceutical company staff. Research-related demands and possible sources of stress for all participants in the process, such as recruiting and maintaining patients in studies, are discussed. Read More