A rare case of pulmonary tuberculosis with simultaneous pulmonary and skin sarcoidosis: a case report.

Authors:
Kornelija Mise
Kornelija Mise
University of Split
Ivana Goic-Barisic
Ivana Goic-Barisic
University of Split
Igor Barisic
Igor Barisic
University of Split
Marija Tonkic
Marija Tonkic
University Hospital Split

Cases J 2010 Jan 13;3:24. Epub 2010 Jan 13.

Department of Clinical Microbiology and School of Medicine University of Split, Split, Croatia.

Background: Tuberculosis and sarcoidosis are chronic diseases that rarely occur concomitantly. Sarcoidosis is a multisystem granulomatous disorder characterized pathologically by the presence of non-caseating granulomas in involved tissues. Tuberculosis is infectious disease caused by Mycobacterium tuberculosis characterized by granulomas with caseous necrosis.

Case Presentation: We present a case of 43-year-old female refugee from Kosovo with microbiological confirmation of pulmonary tuberculosis and pulmonary and skin sarcoidosis at the same time. Three weeks after corticosteroid therapy for pulmonary sarcoidosis was introduced, positive finding of mycobacterium culture of bronchial aspirate was observed. Based on these results, corticosteroid therapy was excluded and antituberculous therapy was introduced for six months. In the meantime, new nodes on face and nose appeared and skin sarcoidosis was diagnosed. The patient was given corticosteroids and colchicine according to the skin and pulmonary sarcoidosis therapy recommendation.

Conclusion: The authors of this study suggest that in cases when there is a dilemma in diagnosis between tuberculosis and sarcoidosis we should advance with corticosteroid therapy until we have microbiological confirmation of mycobacterium culture. This case is remarkable because this is a third described case of sarcoidosis and tuberculosis together (the first reported in Asia, the second in South Africa), and to authors knowledge, this is a first case report in Europe.

Download full-text PDF

Source
http://dx.doi.org/10.1186/1757-1626-3-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822819PMC

Still can't find the full text of the article?

We can help you send a request to the authors directly.
January 2010
11 Reads

Publication Analysis

Top Keywords

skin sarcoidosis
12
corticosteroid therapy
12
sarcoidosis
9
case report
8
pulmonary skin
8
tuberculosis sarcoidosis
8
mycobacterium culture
8
microbiological confirmation
8
pulmonary sarcoidosis
8
pulmonary tuberculosis
8
tuberculosis
7
pulmonary
6
case
5
therapy
5
excluded antituberculous
4
antituberculous therapy
4
therapy introduced
4
therapy excluded
4
based corticosteroid
4
aspirate observed
4

Similar Publications