Complementary acupuncture in Parkinson's disease: a spect study.

Authors:
Dr. Yong Huang, PhD
Dr. Yong Huang, PhD
Guangxi Normal University
GuiIin, Guangxi | China
Xuemei Jiang
Xuemei Jiang
Jinan Infectious Disease Hospital
Ying Zhuo
Ying Zhuo
College of Chemistry and Chemical Engineering
China
Gustav Wik
Gustav Wik
University of Bergen
Norway

Int J Neurosci 2010 Feb;120(2):150-4

School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.

We studied cerebral effects of complementary acupuncture in Parkinson's disease using single photon emission computed tomography (SPECT) measures of 99mTc-ECD and 99mTc-TRODAT-4, before and after five weeks of treatment. Ten patients were randomly assigned to receive levodopa alone (controls) or levodopa and complementary scalp electro-acupuncture. Before treatment, no hemispheric regional cerebral blood flow (rCBF) differences were found, whereas striatal dopamine transporter (DAT) activity was lower in the most affected hemisphere. Treatment with levodopa alone did not change rCBF, whereas it increased basal ganglion DAT activity in the most affected hemisphere. Patients who received levodopa and complementary acupuncture had increased rCBF in the frontal lobe, the occipital lobe, the basal ganglion, and the cerebellum in the most affected hemisphere as compared to baseline, but there were no changes in basal ganglia DAT levels. Thus, complementary acupuncture treatment in Parkinson's disease may affect rCBF but not basal ganglion DAT.

Download full-text PDF

Source
http://dx.doi.org/10.3109/00207450903316527DOI Listing
February 2010
58 Reads

Publication Analysis

Top Keywords

complementary acupuncture
16
parkinson's disease
12
basal ganglion
12
dat activity
8
levodopa complementary
8
acupuncture parkinson's
8
ganglion dat
8
complementary
5
rcbf
4
blood flow
4
rcbf differences
4
differences striatal
4
occipital lobe
4
cerebral blood
4
lobe basal
4
flow rcbf
4
treatment hemispheric
4
scalp electro-acupuncture
4
complementary scalp
4
hemisphere compared
4

References

(Supplied by CrossRef)
Article in Journal of Nuclear Medicine
Alavi A. et al.
Journal of Nuclear Medicine 1993
Article in Parkinsonism and Related Disorders
Booij J. et al.
Parkinsonism and Related Disorders 2007
Article in Journal of Neurology Neurosurgery and Psychiatry
Cheesman A. L. et al.
Journal of Neurology Neurosurgery and Psychiatry 2005
Article in Movement Disorders
Cristian A. et al.
Movement Disorders 2005
Article in Journal of Alternative and Complementary Medicine
Eng M. L. et al.
Journal of Alternative and Complementary Medicine 2006

Gao G. D. et al.
2004
Article in Journal of Neural Transmission
Hesse S. et al.
Journal of Neural Transmission 2006
Article in Neurology
Hoehn M. M. et al.
Neurology 1967
Article in International Journal of Neuroscience
Huang Y. et al.
International Journal of Neuroscience 2007
Article in International Journal of Neuroscience
Huang Y. et al.
International Journal of Neuroscience 2009
Article in International Journal of Neuroscience
Huang Y. et al.
International Journal of Neuroscience

Similar Publications