Uncommon synchronous histopathological features of a radicular cyst: a case report.

Panagiotis Kafas
Panagiotis Kafas
School of Dentistry
Tahwinder Upile
Tahwinder Upile
University College London
United Kingdom
Waseem Jerjes
Waseem Jerjes
University College London
United Kingdom

Cases J 2009 Aug 25;2:9067. Epub 2009 Aug 25.

Department of Oral Surgery and Radiology, School of Dentistry, Aristotle University, Thessalonica, Greece.

Radicular cysts are the most common inflammatory odontogenic cystic lesions. It originates from epithelial residues in periodontal ligaments secondary to inflammation. The pathogenesis involves the activation of epithelial cell rests of Malaseez after physical, chemical or bacterial injury. Microscopically, the cyst is thin with smooth or corrugated inner surface. The most common epithelial lining is stratified squamous; with Rushton's hyaline bodies in 10% of the reported cases. Slow accumulation and deposition of cholesterol during the inflammatory process leads to the formation of "clefts" with acute and chronic inflammatory cells in the proliferating epithelium and connective tissue, respectively. The presence of hemosiderin usually indicates a previous micro-hemorrhage event. While the presence of lipid-laden macrophages or foam cells indicate the presence of cholesterol-removing mechanism from the lesion. We report a rare case of 38-year-old Mediterranean female presented with throbbing right maxillary pain. The diagnosis of radicular cyst was confirmed by the presence of atrophic non-keratinized stratified squamous epithelium. The radicular cyst was associated with hemosiderin, foam cells, subepithelial fibrosis and root canal dystrophic calcification. They represent uncommon synchronous histopathological features.
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http://dx.doi.org/10.1186/1757-1626-0002-0000009067DOI ListingPossible
August 2009
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